The effects of gender on electrical therapies for the heart: Procedural considerations, results and complications

Igor Diemberger, Raffaella Marazzi, Michela Casella, Francesca Vassanelli, Paola Galimberti, Mario Luzi, Alessio Borrelli, Ezio Soldati, Pier Giorgio Golzio, Stefano Fumagalli, Pietro Francia, Luigi Padeletti, Gianluca Botto, Giuseppe Boriani

Research output: Contribution to journalReview article

Abstract

Use of cardiac implantable devices and catheter ablation is steadily increasing in Western countries following the positive results of clinical trials. Despite the advances in scientific knowledge, tools development, and techniques improvement we still have some grey area in the field of electrical therapies for the heart. In particular, several reports highlighted differences both in medical behaviour and procedural outcomes between female and male candidates. Women are referred later for catheter ablation of supraventricular arrhythmias, especially atrial fibrillation, leading to suboptimal results. On the opposite females present greater response to cardiac resynchronization, while the benefit of implantable defibrillator in primary prevention seems to be less pronounced. Differences on aetiology, clinical profile, and development of myocardial scarring are the more plausible causes. This review will discuss all these aspects together with gender-related differences in terms of acute/late complications. We will also provide useful hints on plausible mechanisms and practical procedural aspects.

Original languageEnglish
Pages (from-to)1911-1921
Number of pages11
JournalEuropace
Volume19
Issue number12
DOIs
Publication statusPublished - Dec 1 2017

Fingerprint

Catheter Ablation
Cardiac Catheters
Cardiac Resynchronization Therapy
Indwelling Catheters
Implantable Defibrillators
Primary Prevention
Atrial Fibrillation
Cicatrix
Cardiac Arrhythmias
Clinical Trials
Equipment and Supplies
Therapeutics

Keywords

  • Ablation
  • Arrhythmia
  • CIED
  • Defibrillator
  • Gender
  • Review
  • Sex

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Diemberger, I., Marazzi, R., Casella, M., Vassanelli, F., Galimberti, P., Luzi, M., ... Boriani, G. (2017). The effects of gender on electrical therapies for the heart: Procedural considerations, results and complications. Europace, 19(12), 1911-1921. https://doi.org/10.1093/europace/eux034

The effects of gender on electrical therapies for the heart : Procedural considerations, results and complications. / Diemberger, Igor; Marazzi, Raffaella; Casella, Michela; Vassanelli, Francesca; Galimberti, Paola; Luzi, Mario; Borrelli, Alessio; Soldati, Ezio; Golzio, Pier Giorgio; Fumagalli, Stefano; Francia, Pietro; Padeletti, Luigi; Botto, Gianluca; Boriani, Giuseppe.

In: Europace, Vol. 19, No. 12, 01.12.2017, p. 1911-1921.

Research output: Contribution to journalReview article

Diemberger, I, Marazzi, R, Casella, M, Vassanelli, F, Galimberti, P, Luzi, M, Borrelli, A, Soldati, E, Golzio, PG, Fumagalli, S, Francia, P, Padeletti, L, Botto, G & Boriani, G 2017, 'The effects of gender on electrical therapies for the heart: Procedural considerations, results and complications', Europace, vol. 19, no. 12, pp. 1911-1921. https://doi.org/10.1093/europace/eux034
Diemberger I, Marazzi R, Casella M, Vassanelli F, Galimberti P, Luzi M et al. The effects of gender on electrical therapies for the heart: Procedural considerations, results and complications. Europace. 2017 Dec 1;19(12):1911-1921. https://doi.org/10.1093/europace/eux034
Diemberger, Igor ; Marazzi, Raffaella ; Casella, Michela ; Vassanelli, Francesca ; Galimberti, Paola ; Luzi, Mario ; Borrelli, Alessio ; Soldati, Ezio ; Golzio, Pier Giorgio ; Fumagalli, Stefano ; Francia, Pietro ; Padeletti, Luigi ; Botto, Gianluca ; Boriani, Giuseppe. / The effects of gender on electrical therapies for the heart : Procedural considerations, results and complications. In: Europace. 2017 ; Vol. 19, No. 12. pp. 1911-1921.
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