Dietary-treated phenylketonuric patients (PKUs) display low levels of long-chain polyunsaturated fatty acids (PUFA) in plasma lipids. In a 6-month clinical trial we observed a decrease of triglycerides and an increase of n-3 long-chain PUFA in plasma of PKUs supplemented with fish oil, while no major differences in respect to the baseline values were found in a group supplemented with blackcurrant oil. A more complete source of long-chain PUFA of both the n-6 and n-3 series should be investigated for dietary supplementation of PKU patients.
|Number of pages||4|
|Journal||Prostaglandins, Leukotrienes and Essential Fatty Acids|
|Publication status||Published - 1995|
ASJC Scopus subject areas
- Cell Biology
- Clinical Biochemistry
- Endocrinology, Diabetes and Metabolism