The effects of telmisartan alone or with hydrochlorothiazide on morning and 24-h ambulatory BP control

Results from a practice-based study (SURGE 2)

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Observational studies have shown that 24-h and morning ambulatory blood pressure (BP) control is low. This large-scale, practice-based study evaluated the effects of telmisartan 40 or 80 mg alone or in combination with hydrochlorothiazide (HCTZ) 12.5 mg on these BP parameters over 8 weeks; treatment was adjusted if clinic BP remained ≥140/90 mm Hg. A total of 863 patients were evaluated (baseline mean clinic BP, morning and 24-h ambulatory BP: 155±15/93±10 mm Hg, 137±15/83±11 mm Hg, 133±14/79±10 mm Hg, respectively; 68% were previously treated at baseline). Telmisartan with/without HCTZ significantly reduced the mean morning ambulatory BP (-8.2/-4.9 mm Hg), daytime ambulatory BP (-8.0/-4.7 mm Hg), 24-h ambulatory BP (-7.9/-4.7 mm Hg) and clinic BP (-22.3/-13.2 mm Hg) (all P

Original languageEnglish
Pages (from-to)322-327
Number of pages6
JournalHypertension Research
Volume36
Issue number4
DOIs
Publication statusPublished - Apr 2013

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Hydrochlorothiazide
Blood Pressure
telmisartan
Observational Studies

Keywords

  • ambulatory blood pressure monitoring
  • hydrochlorothiazide
  • morning blood pressure control
  • telmisartan

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "The effects of telmisartan alone or with hydrochlorothiazide on morning and 24-h ambulatory BP control: Results from a practice-based study (SURGE 2)",
abstract = "Observational studies have shown that 24-h and morning ambulatory blood pressure (BP) control is low. This large-scale, practice-based study evaluated the effects of telmisartan 40 or 80 mg alone or in combination with hydrochlorothiazide (HCTZ) 12.5 mg on these BP parameters over 8 weeks; treatment was adjusted if clinic BP remained ≥140/90 mm Hg. A total of 863 patients were evaluated (baseline mean clinic BP, morning and 24-h ambulatory BP: 155±15/93±10 mm Hg, 137±15/83±11 mm Hg, 133±14/79±10 mm Hg, respectively; 68{\%} were previously treated at baseline). Telmisartan with/without HCTZ significantly reduced the mean morning ambulatory BP (-8.2/-4.9 mm Hg), daytime ambulatory BP (-8.0/-4.7 mm Hg), 24-h ambulatory BP (-7.9/-4.7 mm Hg) and clinic BP (-22.3/-13.2 mm Hg) (all P",
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author = "Gianfranco Parati and Grzegorz Bilo and Josep Redon",
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AU - Bilo, Grzegorz

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