We have investigated the effects of stellate ganglion electrostimulation on the perfusion pressure of the coronary vascular bed prfused at constant flow. We always observed systemic hypertension and two kinds of response in the coronary district: vasodilatation or vasoconstriction. These responses were blocked by propranolol and phentolamine i.a. administration respectively, while both the phenomena were blocked by i.v. injection of guanethidine. These results seem to suggest that nervous sympathetic stimulation induces catecholamine release by means of either pregangliae adrenergic fibers directed to coronary vessels or postganglial adrenergic fibers directed to the myocardium. The occurrence of vasodilation or vasoconstriction could be explained by the prevalent stimulation of myocardial or coronary adrenoceptors.
|Number of pages||6|
|Journal||Giornale Italiano di Cardiologia|
|Publication status||Published - 1980|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine