The emerging role of obesity, diet and lipid metabolism in prostate cancer

Matteo Ferro; Daniela Terracciano; Carlo Buonerba; Giuseppe Lucarelli; Danilo Bottero; Sisto Perdonà; Riccardo Autorino; Alessandro Serino; Francesco Cantiello; Rocco Damiano; Iulia Andras; Sabino De Placido; Giuseppe Di Lorenzo; Michele Battaglia; Barbara A. Jereczek-Fossa; Vincenzo Mirone; Ottavio De Cobelli

doi:10.2217/fon-2016-0217

The emerging role of obesity, diet and lipid metabolism in prostate cancer

Matteo Ferro, Daniela Terracciano, Carlo Buonerba, Giuseppe Lucarelli, Danilo Bottero, Sisto Perdonà, Riccardo Autorino, Alessandro Serino, Francesco Cantiello, Rocco Damiano, Iulia Andras, Sabino De Placido, Giuseppe Di Lorenzo, Michele Battaglia, Barbara A. Jereczek-Fossa, Vincenzo Mirone, Ottavio De Cobelli

Istituto Nazionale Tumori Fondazione G. Pascale

Research output: Contribution to journal › Review article › peer-review

Abstract

Obesity is associated with an increased risk of a number of serious medical conditions, including cancer. As far as prostate cancer is concerned, obesity is associated with an increased risk of high-grade tumors, which is possibly related to lower androgen levels. Diet may also affect prostate cancer risk since countries with a higher dietary fat intake also present higher prostate cancer mortality rates. Interestingly, prostate cancer is associated with a number of metabolic alterations that may provide valuable diagnostic and therapeutic targets. This review explores the available clinical as well as biological evidence supporting the relationship between obesity, diet, alteration in metabolic pathways and prostate cancer.

Original language	English
Pages (from-to)	285-293
Number of pages	9
Journal	Future Oncology
Volume	13
Issue number	3
DOIs	https://doi.org/10.2217/fon-2016-0217
Publication status	Published - Feb 1 2017

Keywords

diet
obesity
urologic/prostate

ASJC Scopus subject areas

Oncology
Cancer Research

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Ferro, M., Terracciano, D., Buonerba, C., Lucarelli, G., Bottero, D., Perdonà, S., Autorino, R., Serino, A., Cantiello, F., Damiano, R., Andras, I., Placido, S. D., Di Lorenzo, G., Battaglia, M., Jereczek-Fossa, B. A., Mirone, V., & De Cobelli, O. (2017). The emerging role of obesity, diet and lipid metabolism in prostate cancer. Future Oncology, 13(3), 285-293. https://doi.org/10.2217/fon-2016-0217

Ferro, M, Terracciano, D, Buonerba, C, Lucarelli, G, Bottero, D, Perdonà, S, Autorino, R, Serino, A, Cantiello, F, Damiano, R, Andras, I, Placido, SD, Di Lorenzo, G, Battaglia, M, Jereczek-Fossa, BA, Mirone, V & De Cobelli, O 2017, 'The emerging role of obesity, diet and lipid metabolism in prostate cancer', Future Oncology, vol. 13, no. 3, pp. 285-293. https://doi.org/10.2217/fon-2016-0217

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AU - Perdonà, Sisto

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The emerging role of obesity, diet and lipid metabolism in prostate cancer

Abstract

Keywords

ASJC Scopus subject areas

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