TY - JOUR
T1 - The EORTC module for quality of life in patients with thyroid cancer
T2 - Phase III
AU - Singer, Susanne
AU - Jordan, Susan
AU - Locati, Laura D.
AU - Pinto, Monica
AU - Tomaszewska, Iwona M.
AU - Araújo, Cláudia
AU - Hammerlid, Eva
AU - Vidhubala, E.
AU - Husson, Olga
AU - Kiyota, Naomi
AU - Brannan, Christine
AU - Salem, Dina
AU - Gamper, Eva M.
AU - Arraras, Juan Ignacio
AU - Ioannidis, Georgios
AU - Andry, Guy
AU - Inhestern, Johanna
AU - Grégoire, Vincent
AU - Licitra, Lisa
PY - 2017/4/1
Y1 - 2017/4/1
N2 - The purpose of the study was to pilot-test a questionnaire measuring healthrelated quality of life (QoL) in thyroid cancer patients to be used with the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire EORTC QLQ-C30. A provisional questionnaire with 47 items was administered to patients treated for thyroid cancer within the last 2 years. Patients were interviewed about time and help needed to complete the questionnaire, and whether they found the items understandable, confusing or annoying. Items were kept in the questionnaire if they fulfilled pre-defined criteria: relevant to the patients, easy to understand, not confusing, few missing values, neither floor nor ceiling effects, and high variance. A total of 182 thyroid cancer patients in 15 countries participated (n = 115 with papillary, n = 31 with follicular, n = 22 with medullary, n = 6 with anaplastic, and n = 8 with other types of thyroid cancer). Sixty-six percent of the patients needed 15 min or less to complete the questionnaire. Of the 47 items, 31 fulfilled the predefined criteria and were kept unchanged, 14 were removed, and 2 were changed. Shoulder dysfunction was mentioned by 5 patients as missing and an item covering this issue was added. To conclude, the EORTC quality of life module for thyroid cancer (EORTC QLQ-THY34) is ready for the final validation phase IV.
AB - The purpose of the study was to pilot-test a questionnaire measuring healthrelated quality of life (QoL) in thyroid cancer patients to be used with the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire EORTC QLQ-C30. A provisional questionnaire with 47 items was administered to patients treated for thyroid cancer within the last 2 years. Patients were interviewed about time and help needed to complete the questionnaire, and whether they found the items understandable, confusing or annoying. Items were kept in the questionnaire if they fulfilled pre-defined criteria: relevant to the patients, easy to understand, not confusing, few missing values, neither floor nor ceiling effects, and high variance. A total of 182 thyroid cancer patients in 15 countries participated (n = 115 with papillary, n = 31 with follicular, n = 22 with medullary, n = 6 with anaplastic, and n = 8 with other types of thyroid cancer). Sixty-six percent of the patients needed 15 min or less to complete the questionnaire. Of the 47 items, 31 fulfilled the predefined criteria and were kept unchanged, 14 were removed, and 2 were changed. Shoulder dysfunction was mentioned by 5 patients as missing and an item covering this issue was added. To conclude, the EORTC quality of life module for thyroid cancer (EORTC QLQ-THY34) is ready for the final validation phase IV.
KW - Anaplastic
KW - Follicular
KW - Medullary
KW - Papillary
KW - Patient-reported outcomes
KW - Quality of life
KW - Thyroid cancer
UR - http://www.scopus.com/inward/record.url?scp=85017662228&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017662228&partnerID=8YFLogxK
U2 - 10.1530/ERC-16-0530
DO - 10.1530/ERC-16-0530
M3 - Article
AN - SCOPUS:85017662228
VL - 24
SP - 197
EP - 207
JO - Endocrine-Related Cancer
JF - Endocrine-Related Cancer
SN - 1351-0088
IS - 4
ER -