The epidemiology of epilepsy in Europe - A systematic review

Lars Forsgren, E. Beghi, A. Õun, M. Sillanpää

Research output: Contribution to journalArticle

461 Citations (Scopus)

Abstract

Population-based epidemiological studies on epilepsy are available mainly from the UK and the Nordic, Baltic and western Mediterranean countries. No studies were identified from large areas of Europe, especially from the former eastern Europe (except the Baltic countries) and the eastern Mediterranean countries. Based on the prevalence of epilepsy in different studies and accounting for incomplete case identification the estimated number of children and adolescents in Europe with active epilepsy is 0.9 million (prevalence 4.5-5.0 per 1000), 1.9 million in ages 20-64 years (prevalence six per 1000) and 0.6 million in ages 65 years and older (prevalence seven per 1000). Approximately 20-30% of the epilepsy population have more than one seizure per month. Based on the age-specific incidence rates in European studies, the estimated number of new cases per year amongst European children and adolescents is 130 000 (incidence rate 70 per 100 000), 96 000 in adults 20-64 years (incidence rate 30 per 100 000) and 85 000 in the elderly 65 years and older (incidence 100 per 100 000). The proportion of both new and established cases with epilepsy in the young, adults and elderly in individual countries may differ substantially from total European distribution because of differences in age structure.

Original languageEnglish
Pages (from-to)245-253
Number of pages9
JournalEuropean Journal of Neurology
Volume12
Issue number4
DOIs
Publication statusPublished - Apr 2005

Fingerprint

Epilepsy
Epidemiology
Incidence
Eastern Europe
Population
Epidemiologic Studies
Young Adult
Seizures

Keywords

  • Epidemiology
  • Epilepsy
  • Etiology
  • Europe
  • Frequency
  • Incidence
  • Prevalence
  • Review
  • Seizure
  • Seizures

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

The epidemiology of epilepsy in Europe - A systematic review. / Forsgren, Lars; Beghi, E.; Õun, A.; Sillanpää, M.

In: European Journal of Neurology, Vol. 12, No. 4, 04.2005, p. 245-253.

Research output: Contribution to journalArticle

Forsgren, Lars ; Beghi, E. ; Õun, A. ; Sillanpää, M. / The epidemiology of epilepsy in Europe - A systematic review. In: European Journal of Neurology. 2005 ; Vol. 12, No. 4. pp. 245-253.
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