The european hematology association roadmap for european hematology research: A consensus document

Andreas Engert, Carlo Balduini, A. Brand, Bertrand Coiffier, Catherine Cordonnier, Hartmut Döhner, Thom Duyvené De Wit, Sabine Eichinger, W. E. Fibbe, Tony Green, Fleur De Haas, Achille Iolascon, Thierry Jaffredo, F. Rodeghiero, Gilles Sall Es, Jan Jacob Schuringa, Marc P E André, Isabelle André-Schmutz, A. Bacigalupo, Pierre Yves BochudMonique L. Den Boer, Chiara Bonini, Clara Camaschella, Andrew J. Cant, Maria Domenica Cappellini, Mario Cazzola, C. L. Celso, M. Dimopoulos, L. Douay, Elaine Dzierzak, Hermann Einsele, Andres Ferreri, Lucia De Franceschi, P. Gaulard, Berthold Gottgens, Andreas Greinacher, Paolo Gresele, John G. Gribben, Gerald De Haan, John Bjarne Hansen, A. Hochhaus, Rezan A. Kadir, Srinivas Kaveri, Valerie Kouskoff, Thomas Kühne, Paul Alexander Kyrle, Per Ljungman, G. Maschmeyer, Simón Méndez-Ferrer, Michael Milsom, Christine Mummery, Gert J. Ossenkoppele, Alessandro Pecci, Flora Peyvandi, S. Philipsen, Pieter H. Reitsma, J. M. Ribera, Antonio Risitano, Stefano Rivella, Wolfram Ruf, Timm Schroeder, M. A. Scully, Gerard Sociè, Frank Staal, Simon Stanworth, Reinhard Stauder, Stephan Stilgenbauer, H. Tamary, Kim Theilgaard-Mönch, Swee Lay Thein, Hervé Tilly, M. Trneny, William Vainchenker, Alessandro M. Vannucchi, Claudio Viscoli, H. Vrielink, Hans Zaaijer, Alberto Zanella, Lello Zolla, J. J. Zwaginga, Patricia Aguilar Martinez, Emile Van Den Akker, Shubha Allard, Nicholas P. Anagnou, Immacolata Andolfo, Jean Christophe Andrau, E. Angelucci, David Anstee, I. Aurer, Hervé Avet-Loiseau, Yesim Aydinok, Tamam Bakchoul, A. Balduini, Wilma Barcellini, Dominique Baruch, André Baruchel, Jagadeesh Bayry, Celeste Bento, Anke van den Berg, Rosa Bernardi, Paola Bianchi, Anna Bigas, A. Biondi, Milos Bohonek, Dominique Bonnet, Peter Borchmann, Niels Borregaard, S. K. Braekkan, Marcel R M van den Brink, Ellen Brodin, Lars Bullinger, Christian Buske, Barbara Butzeck, Jörg Cammenga, Elias Campo, Antonino Carbone, F. Cervantes, S. Cesaro, Pierre Charbord, F. H J Claas, Hannah Cohen, Jacqueline Conard, Paul Coppo, Joan Lluis Vives Corron, Lydie Da Costa, Frederic Davi, Ruud Delwel, I. Dianzani, Dragoslav Domanović, Peter Donnelly, Tadeja Dovč Drnovšek, Martin H. Dreyling, Ming Qing Du, Carlo Dufour, Charles Durand, Dimitar G. Efremov, Androulla Eleftheriou, Jacques Elion, Marieke Emonts, Monika Engelhardt, Sophie Ezine, Fred Falkenburg, Remi Favier, Massimo Federico, Pierre Fenaux, Jude Fitzgibbon, Johan Flygare, Robin Foà, Lesley Forrester, Frederic Galacteros, Isabella Garagiola, Chris Gardiner, Olivier Garraud, Christel Van Geet, Hartmut Geiger, J. Geissler, Ulrich Germing, Cedric Ghevaert, Domenico Girelli, Bertrand Godeau, Nicola Gökbuget, Hartmut Goldschmidt, A. Goodeve, Thomas Graf, Giovanna Graziadei, Martin Griesshammer, Yves Gruel, F. Guilhot, Stephan Von Gunten, I. C. Gyssens, Joerg P. Halter, Claire N. Harrison, Cornelis L. Harteveld, Eva Hellström-Lindberg, Olivier Hermine, Douglas Higgs, Peter Hillmen, H. H. Hirsch, P. Hoskin, Gerwin Huls, A. Inati, Peter Johnson, Antonis Kattamis, V. Kiefel, Marina Kleanthous, Hannes Klump, Daniela Krause, Johanna Kremer Hovinga, Georges Lacaud, S. Lacroix-Desmazes, Judith Landman-Parker, Steven LeGouill, Georg Lenz, M. Von Lilienfeld-Toal, M. von Lindern, Armando López-Guillermo, Enrico Lopriore, M. Lozano, Elizabeth Macintyre, Michael Makris, C. Mannhalter, Joost H A Martens, Stephan Mathas, Axel Matzdorff, Alexander Medvinsky, Pablo Menendez, A. R. Migliaccio, Kenichi Miharada, Malgorzata Mikulska, Véronique Minard, Carlos Montalbán, Mariane De Montalembert, Emili Montserrat, P. E. Morange, Joanne Mountford, Martina Muckenthaler, Carsten Müller-Tidow, Andrew Mumford, Bertrand Nadel, José Tomás Navarro, Wassim El Nemer, France Noizat-Pirenne, Brian O’Mahony, J. Oldenburg, Martin Olsson, Robert Oostendorp, A. Palumbo, Francesco Passamonti, Roger Patient, Regis Peffault de Latour, Francoise Pflumio, L. Pierelli, Antonio Piga, D. Pollard, Marc Raaijmakers, J. Radford, Ralf Rambach, A. Koneti Rao, Hana Raslova, Paolo Rebulla, David C. Rees, Vincent Ribrag, Anita Rijneveld, Sara Rinalducci, Tadeusz Robak, I. Roberts, Charlene Rodrigues, F. R. Rosendaal, Andreas Rosenwald, S. Rule, Roberta Russo, G. Saglio, Mayka Sanchez, R. E. Scharf, Peter Schlenke, John Semple, Jorge Sierra, Cynthia So-Osman, José Manuel Soria, Kostas Stamatopoulos, Bernd Stegmayr, Hendrik G. Stunnenberg, Dorine W. Swinkels, João Pedro Taborda Barata, Tom Taghon, Ali T. Taher, Evangelos Terpos, Jecko Thachil, Jean Daniel Tissot, Ivo P. Touw, Ash Toye, Ralf Trappe, A. Traverse-Glehen, Sule Unal, Sophie Vaulont, Vip Viprakasit, U. Vitolo, R. Van Wijk, Agnieszka Wójtowicz, Sacha Zeerleder, Barbara Zieger

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Abstract

The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at ∈ European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better fu treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine ‘sections’ in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.

Original languageEnglish
Pages (from-to)115-208
Number of pages94
JournalHaematologica
Volume101
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

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ASJC Scopus subject areas

  • Hematology

Cite this

Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Döhner, H., De Wit, T. D., Eichinger, S., Fibbe, W. E., Green, T., De Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Sall Es, G., Schuringa, J. J., André, M. P. E., André-Schmutz, I., Bacigalupo, A., ... Zieger, B. (2016). The european hematology association roadmap for european hematology research: A consensus document. Haematologica, 101(2), 115-208. https://doi.org/10.3324/haematol.2015.136739