The evaluation of determinants and impacts of co-production in healthcare: A research protocol for opat in cystic fibrosis

Marta Marsilio, Andrea Gramegna, Floriana Fusco, Eleonora Gheduzzi, Giovanna Pizzamiglio, Francesco Blasi, Chiara Guglielmetti

Research output: Contribution to journalArticlepeer-review


Introduction: Co-production is more and more considered as a promising tool for dealing with the main challenges in the health sector (e.g., growing rates of chronic diseases, budget constraints, higher patients’ expectations of the quality and the value of services, equity to access of care, etc.). However, there is still little evidence on co-production determinants and impacts. Description: This research protocol aims to present a framework to assess the determinants and impacts of the co-productive approach in healthcare delivery on patients, professionals, and providers from economic, organisational, and clinical perspectives. To this end, the paper examines the co-produced outpatient parenteral antimicrobial therapy (OPAT), applied to cystic fibrosis patients in an Italian hospital. A mixed methods approach will be adopted and data will be collected through semi-structured interviews and surveys of patients, caregivers, and professionals; biological samples of patients; archival sources. Then, the analyses to be performed are the following: (i) cost evaluation, (ii) content, (iii) descriptive and inferential statistical, (iv) microbiome analysis, and (v) desk analysis. Conclusion: The research protocol contributes to both theoretical and practical knowledge. It represents the first attempt to develop a systematic analytical framework for the evaluation of co-production in healthcare. Moreover, the findings gathered within the study will provide evidence to support policy makers and managers in decision-making and managerial processes within the health service.

Original languageEnglish
Article number15
JournalInternational Journal of Integrated Care
Issue number2
Publication statusPublished - Apr 30 2021


  • Co-production
  • Cystic fibrosis
  • Determinants
  • Evaluation
  • Health
  • Impact
  • OPAT

ASJC Scopus subject areas

  • Health(social science)
  • Sociology and Political Science
  • Health Policy


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