Valutazione del metabolismo lipidico in giovani pazienti ipotiroidei sottoposti a terapia col L-4

Translated title of the contribution: The evaluation of lipid metabolism in young patients with hypothyroidism and L-4 treatment

G. Lupoli, B. Cassese, G. Vitale, E. Rampone, M. R. Fittipaldi, B. Oliviero, C. Guerriero, G. Riccardi

Research output: Contribution to journalArticlepeer-review

Abstract

The aims of this study were to evaluate the type and frequency of hyperlipidemia and the effects of levo-thyroxine on lipid metabolism in hypothyroidism. In 93 patients with hypothyroidism lipid profile, TSH, FT3, FT4, were measured before and after thyroid hormone replacement therapy. Before treatment 74 patients had type IIa hyperlipidemia, 15 patients had type IIb hyperlipidemia and 4 patients had normal lipid values. We observed a significant reduction of total cholesterol, LDL, HDL values after the therapy, whereas, at this time, no difference could be detected for serum triglycerides levels. In conclusion hypercolesterolemia elicited by hypothyroidism is potentially reversible by restoration of the euthyroid state.

Translated title of the contributionThe evaluation of lipid metabolism in young patients with hypothyroidism and L-4 treatment
Original languageItalian
Pages (from-to)347-349
Number of pages3
JournalQuaderni di Medicina e Chirurgia
Volume12
Issue number4
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Surgery

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