The evaluation of right ventricular performance in different clinical models of heart failure

Carlo Campana, Michele Pasotti, Lorenzo Monti, Miriam Revera, Alessandra Serio, Luisa Nespoli, Giulia Magrini, Laura Scelsi, Stefano Ghio, Luigi Tavazzi

Research output: Contribution to journalArticle

Abstract

To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7% and 18 ± 9%; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.

Original languageEnglish
JournalEuropean Heart Journal, Supplement
Volume6
Issue number6
DOIs
Publication statusPublished - Nov 2004

Fingerprint

Brain Natriuretic Peptide
Heart Failure
Right Ventricular Function
Cardiac Catheterization
Pulmonary Hypertension
Stroke Volume
Echocardiography
Thermodilution
Pulmonary Wedge Pressure
Atrial Pressure
Hemodynamics

Keywords

  • BNP
  • End-stage heart failure
  • Pulmonary hypertension
  • Right ventricular function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The evaluation of right ventricular performance in different clinical models of heart failure. / Campana, Carlo; Pasotti, Michele; Monti, Lorenzo; Revera, Miriam; Serio, Alessandra; Nespoli, Luisa; Magrini, Giulia; Scelsi, Laura; Ghio, Stefano; Tavazzi, Luigi.

In: European Heart Journal, Supplement, Vol. 6, No. 6, 11.2004.

Research output: Contribution to journalArticle

@article{eba9a1dc0e784253b5b1d6370ae365d5,
title = "The evaluation of right ventricular performance in different clinical models of heart failure",
abstract = "To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7{\%} and 18 ± 9{\%}; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.",
keywords = "BNP, End-stage heart failure, Pulmonary hypertension, Right ventricular function",
author = "Carlo Campana and Michele Pasotti and Lorenzo Monti and Miriam Revera and Alessandra Serio and Luisa Nespoli and Giulia Magrini and Laura Scelsi and Stefano Ghio and Luigi Tavazzi",
year = "2004",
month = "11",
doi = "10.1016/j.ehjsup.2004.09.012",
language = "English",
volume = "6",
journal = "European Heart Journal, Supplement",
issn = "1520-765X",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - The evaluation of right ventricular performance in different clinical models of heart failure

AU - Campana, Carlo

AU - Pasotti, Michele

AU - Monti, Lorenzo

AU - Revera, Miriam

AU - Serio, Alessandra

AU - Nespoli, Luisa

AU - Magrini, Giulia

AU - Scelsi, Laura

AU - Ghio, Stefano

AU - Tavazzi, Luigi

PY - 2004/11

Y1 - 2004/11

N2 - To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7% and 18 ± 9%; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.

AB - To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7% and 18 ± 9%; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.

KW - BNP

KW - End-stage heart failure

KW - Pulmonary hypertension

KW - Right ventricular function

UR - http://www.scopus.com/inward/record.url?scp=8644289475&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8644289475&partnerID=8YFLogxK

U2 - 10.1016/j.ehjsup.2004.09.012

DO - 10.1016/j.ehjsup.2004.09.012

M3 - Article

AN - SCOPUS:8644289475

VL - 6

JO - European Heart Journal, Supplement

JF - European Heart Journal, Supplement

SN - 1520-765X

IS - 6

ER -