Translated title of the contribution: The evaluation with Magnetic Resonance of Agyria-pachigyria complex

B. Bernardi, C. Fonda

Research output: Contribution to journalArticlepeer-review


The Magnetic Resonance Imaging (MRI or MR) of 11 patients with Lissencephaly type 1 were performed on a 0.5 T system. The purpose was to evaluate the ability of MRI to detect the macroscopic morphologic abnormalities and to evaluate their MR appearances. Multiplanar and different MR sequences are needed to delineate all structural macroscopic alterations in agyria-pachigyria complex as basis for clinical coasideratians. The Spin Echo (SE), TI, proton density (PD), T2 weighted, Inversion Recovery (IR) and Gradient Echo (GE) 2D and 3D sequences show differently the cortical and subcortical structures. The laminar necrosis and gliosis is well shown in IR (hypointense rim) and T2-weighted images (hyperintense rim). The coronal 3D GE images with slice thickness of 1 mm, delineate the degree of incomplete inversion of hippocampal region. MR evaluation, especially with high resoluzion TI weighted imaging shows more quantitative criteria for diagnosis and delineation. The morphologic criteria of agyria-pachigyria complex were divided in primary finding, necessary to diagnosis, and secondery findings.

Translated title of the contributionThe evaluation with Magnetic Resonance of Agyria-pachigyria complex
Original languageItalian
Pages (from-to)296-298
Number of pages3
JournalRivista di Neuroradiologia
Issue number2
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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