The evoked potentials score improves the identification of benign MS without cognitive impairment

N. Margaritella, L. Mendozzi, F. Tronci, E. Colicino, M. Garegnani, R. Nemni, E. Gilardi, L. Pugnetti

Research output: Contribution to journalArticlepeer-review

Abstract

Background and purpose: The presence of cognitive impairments (CI) among Benign MS (BMS) patients has challenged actual BMS criteria. We hypothesized that a low evoked potentials score (EP-score) at first neurological evaluation would help identify BMS patients without CI. Methods: The EP-score was retrospectively computed in 29 putative BMS patients who were then tested for CI during 2012. The difference in the prevalence of CI between low EP-score patients and the recent literature was assessed using resampling methods. Results: Among 23 low EP-score patients, only 3 (13%) had CI. This percentage was significantly reduced (P-values 0.05-0.005) compared to recent literature (39-46%). Conclusion: We conclude that a low EP-score at first neurological evaluation successfully helps to identify BMS patients without CI.

Original languageEnglish
Pages (from-to)1423-1425
Number of pages3
JournalEuropean Journal of Neurology
Volume20
Issue number10
DOIs
Publication statusPublished - Oct 2013

Keywords

  • Benign MS
  • Cognition
  • Evoked potentials
  • Evoked potentials score
  • Multiple sclerosis
  • Resampling methods

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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