The evolution of the conservative approach to breast cancer

Alberto Luini, Giovanna Gatti, Stefano Zurrida, Nina Talakhadze, Fabricio Brenelli, Daniela Gilardi, Giovanni Paganelli, Roberto Orecchia, Enrico Cassano, Giuseppe Viale, Claudia Sangalli, Bettina Ballardini, Gabriela Rosali dos Santos, Umberto Veronesi

Research output: Contribution to journalArticlepeer-review


The profound revolution that surgical treatment of breast cancer has undergone during the past 30 years has led to the progressive reduction of the extent of surgery, with less mutilation. As a consequence, quality of life has improved and women are now more motivated to follow screening programs for early diagnosis of the disease. Since conservative surgery is as effective as radical surgery, research is now focused on reducing radiotherapy. Overall, survival after breast cancer is not affected by reducing the extent of surgery, which, together with less invasive diagnostic procedures, has a good effect on patients' quality of life. For this reason in our Institute we are now evaluating the feasibility of a reduction of the radiation field and the sensibility and sensitivity of new diagnostic approaches for axillary staging.

Original languageEnglish
Pages (from-to)120-129
Number of pages10
Issue number2
Publication statusPublished - Apr 2007


  • Breast cancer
  • Conservative treatment
  • Radiotherapy
  • Surgery

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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