Abstract
Childhood cancer is rare, representing only 1% of the total cancer problem. Of children diagnosed with cancer today, more than 70% are predicted to be long-term survivors. Essentially all pediatric cancers are treated by interdigitating radiation with surgical resection and systemic chemotherapy. The use of irradiation, important to achieve high rates of disease local control, must be always balanced against late effects specifically related to this treatment modality, principally growth retardation and second tumors induction. Using neuroblastoma Wilms' tumor and rhabdomyosarcoma as examples, the advances in the optimal multimodality treatment of childhood cancer and the evolution of the role of radiation therapy are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 270-273 |
| Number of pages | 4 |
| Journal | Tumori |
| Volume | 84 |
| Issue number | 2 |
| Publication status | Published - Mar 1998 |
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Keywords
- Childhood cancer
- Combined modality treatment
- Radiotherapy
ASJC Scopus subject areas
- Cancer Research
Cite this
The evolving role of radiation therapy in the optimal multimodality treatment of childhood cancer. / Lombardi, Fabrizio; Navarria, Pierina; Gandola, Lorenza.
In: Tumori, Vol. 84, No. 2, 03.1998, p. 270-273.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The evolving role of radiation therapy in the optimal multimodality treatment of childhood cancer
AU - Lombardi, Fabrizio
AU - Navarria, Pierina
AU - Gandola, Lorenza
PY - 1998/3
Y1 - 1998/3
N2 - Childhood cancer is rare, representing only 1% of the total cancer problem. Of children diagnosed with cancer today, more than 70% are predicted to be long-term survivors. Essentially all pediatric cancers are treated by interdigitating radiation with surgical resection and systemic chemotherapy. The use of irradiation, important to achieve high rates of disease local control, must be always balanced against late effects specifically related to this treatment modality, principally growth retardation and second tumors induction. Using neuroblastoma Wilms' tumor and rhabdomyosarcoma as examples, the advances in the optimal multimodality treatment of childhood cancer and the evolution of the role of radiation therapy are discussed.
AB - Childhood cancer is rare, representing only 1% of the total cancer problem. Of children diagnosed with cancer today, more than 70% are predicted to be long-term survivors. Essentially all pediatric cancers are treated by interdigitating radiation with surgical resection and systemic chemotherapy. The use of irradiation, important to achieve high rates of disease local control, must be always balanced against late effects specifically related to this treatment modality, principally growth retardation and second tumors induction. Using neuroblastoma Wilms' tumor and rhabdomyosarcoma as examples, the advances in the optimal multimodality treatment of childhood cancer and the evolution of the role of radiation therapy are discussed.
KW - Childhood cancer
KW - Combined modality treatment
KW - Radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=0031749818&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031749818&partnerID=8YFLogxK
M3 - Article
C2 - 9620256
AN - SCOPUS:0031749818
VL - 84
SP - 270
EP - 273
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 2
ER -