The first report of late stent thrombosis leading to acute myocardial infarction in patient receiving the new endothelial progenitor cell capture stent

Marco L. Rossi, Dennis Zavalloni, Gabriele L. Gasparini, Ruggiero Mango, Guido Belli, Patrizia Presbitero

Research output: Contribution to journalArticle

Abstract

The endothelial progenitor cell (EPC) capture stent is a stainless steel coronary stent covered with antibodies specific to EPC's surface antigens, designed to promote the faster formation of a functional endothelial lining. This may prevent both stent thrombosis and restenosis as well as reduce the need of prolonged double antiplatelet therapy. Here we report a case of late (156 days after implantation) EPC capture stent thrombosis and re-stenosis of a second EPC capture stent occurring both in the same patient after withdrawal of clopidogrel. Intravascular ultrasound performed during his acute admission showed undersizing of the stent with thrombosis. The present case raises the question about the safety of the EPC capture stent and the need to prolong at least for 6 months double antiplatelet therapy also in patients receiving this new stent.

Original languageEnglish
JournalInternational Journal of Cardiology
Volume141
Issue number1
DOIs
Publication statusPublished - May 14 2010

    Fingerprint

Keywords

  • Angioplasty
  • Clopidogrel
  • Endothelial progenitor cell capture stent
  • Late stent thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this