Lo studio funzionale della corteccia cerebrale mediante la topografia ottica nel neonato

Translated title of the contribution: The functional study of neonatal cerebral cortex by means of optical topography

Andrea Clarici, Stefano Bembich, Laura Travan, Chiara Oretti, Cristina Vecchiet, Michele Bava, Pierpaolo Brovedani, Elena Neri, Stefano Massaccesi, Teresa Farroni, Sergio Demarini

Research output: Contribution to journalArticlepeer-review

Abstract

Optical topography is a non-invasive functional brain imaging technique, which uses light in the near infra-red spectrum and allows to detect hemodynamic changes in the cerebral cortex. Specifically, it measures relative changes in oxygenated, de-oxygenated and total haemoglobin concentrations, reflecting variations in the cerebral blood flow and volume. This technique does not need sedation and it is safe: consequently, it appears particularly feasible to study cerebral neonatal development. Neonatal cerebral cortex activations associated both with simple sensory stimuli and with more complex cognitive or affective-relational have been detected. In neonatology, a promising research field is related to the detection of cerebral hemodynamic response observed in specific conditions (such as encephalopathies and perinatal asphyxia).

Translated title of the contributionThe functional study of neonatal cerebral cortex by means of optical topography
Original languageItalian
Pages (from-to)41-46
Number of pages6
JournalMedico e Bambino
Volume29
Issue number1
Publication statusPublished - Jan 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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