Optical topography is a non-invasive functional brain imaging technique, which uses light in the near infra-red spectrum and allows to detect hemodynamic changes in the cerebral cortex. Specifically, it measures relative changes in oxygenated, de-oxygenated and total haemoglobin concentrations, reflecting variations in the cerebral blood flow and volume. This technique does not need sedation and it is safe: consequently, it appears particularly feasible to study cerebral neonatal development. Neonatal cerebral cortex activations associated both with simple sensory stimuli and with more complex cognitive or affective-relational have been detected. In neonatology, a promising research field is related to the detection of cerebral hemodynamic response observed in specific conditions (such as encephalopathies and perinatal asphyxia).
|Translated title of the contribution||The functional study of neonatal cerebral cortex by means of optical topography|
|Number of pages||6|
|Journal||Medico e Bambino|
|Publication status||Published - Jan 2010|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health