TY - JOUR
T1 - Lo studio funzionale della corteccia cerebrale mediante la topografia ottica nel neonato
AU - Clarici, Andrea
AU - Bembich, Stefano
AU - Travan, Laura
AU - Oretti, Chiara
AU - Vecchiet, Cristina
AU - Bava, Michele
AU - Brovedani, Pierpaolo
AU - Neri, Elena
AU - Massaccesi, Stefano
AU - Farroni, Teresa
AU - Demarini, Sergio
PY - 2010/1
Y1 - 2010/1
N2 - Optical topography is a non-invasive functional brain imaging technique, which uses light in the near infra-red spectrum and allows to detect hemodynamic changes in the cerebral cortex. Specifically, it measures relative changes in oxygenated, de-oxygenated and total haemoglobin concentrations, reflecting variations in the cerebral blood flow and volume. This technique does not need sedation and it is safe: consequently, it appears particularly feasible to study cerebral neonatal development. Neonatal cerebral cortex activations associated both with simple sensory stimuli and with more complex cognitive or affective-relational have been detected. In neonatology, a promising research field is related to the detection of cerebral hemodynamic response observed in specific conditions (such as encephalopathies and perinatal asphyxia).
AB - Optical topography is a non-invasive functional brain imaging technique, which uses light in the near infra-red spectrum and allows to detect hemodynamic changes in the cerebral cortex. Specifically, it measures relative changes in oxygenated, de-oxygenated and total haemoglobin concentrations, reflecting variations in the cerebral blood flow and volume. This technique does not need sedation and it is safe: consequently, it appears particularly feasible to study cerebral neonatal development. Neonatal cerebral cortex activations associated both with simple sensory stimuli and with more complex cognitive or affective-relational have been detected. In neonatology, a promising research field is related to the detection of cerebral hemodynamic response observed in specific conditions (such as encephalopathies and perinatal asphyxia).
KW - Functional neuroimaging
KW - Near infra-red spectroscopy
KW - Neonatal brain
KW - Optical topography
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M3 - Articolo
AN - SCOPUS:76149123608
VL - 29
SP - 41
EP - 46
JO - Medico e Bambino
JF - Medico e Bambino
SN - 1591-3090
IS - 1
ER -