The future of transcatheter mitral valve interventions: Competitive or complementary role of repair vs. Replacement?

Francesco Maisano, Ottavio Alfieri, Shmuel Banai, Maurice Buchbinder, Antonio Colombo, Volkmar Falk, Ted Feldman, Olaf Franzen, Howard Herrmann, Saibal Kar, Karl Heinz Kuck, Georg Lutter, Michael Mack, Georg Nickenig, Nicolo Piazza, Mark Reisman, Carlos E. Ruiz, Joachim Schofer, Lars Søndergaard, Gregg W. StoneMaurizio Taramasso, Martyn Thomas, Alec Vahanian, John Webb, Stephan Windecker, Martin B. Leon

Research output: Contribution to journalArticlepeer-review


Transcatheter mitral interventions has been developed to address an unmet clinical need and may be an alternative therapeutic option to surgery with the intent to provide symptomatic and prognostic benefit. Beyond MitraClip therapy, alternative repair technologies are being developed to expand the transcatheter intervention armamentarium. Recently, the feasibility of transcatheter mitral valve implantation in native non-calcified valves has been reported in very high-risk patients. Acknowledging the lack of scientific evidence to date, it is difficult to predict what the ultimate future role of transcatheter mitral valve interventions will be. The purpose of the present report is to review the current state-of-the-art of mitral valve intervention, and to identify the potential future scenarios, which might benefit most from the transcatheter repair and replacement devices under development.

Original languageEnglish
Pages (from-to)1651-1659
Number of pages9
JournalEuropean Heart Journal
Issue number26
Publication statusPublished - 2015


  • Transcatheter mitral implantation
  • Transcatheter mitral intervention
  • Transcatheter mitral repair

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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