The gallium-deferoxamine complex: Stability with different deferoxamine concentrations and incubation conditions

C. CaracO', L. Aloj, W. C. Eckelman

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Previous studies report that deferoxamine (DFO) binds metallic ions such as Fe3+, In3+ and Ga3+ with very high affinity. This property of DFO has been utilized to label DFO-coupled compounds with radiometals such as 67Ga and 111In. We have studied the effect of low DFO concentrations and of different incubation conditions on the stability of the 67Ga-DFO complex. In our experience high (> 5 μM) DFO concentration appears to be critical in obtaining high radiochemical purity of such complexes.

Original languageEnglish
Pages (from-to)1477-1479
Number of pages3
JournalApplied Radiation and Isotopes
Volume49
Issue number12
DOIs
Publication statusPublished - Dec 1 1998

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The gallium-deferoxamine complex : Stability with different deferoxamine concentrations and incubation conditions. / CaracO', C.; Aloj, L.; Eckelman, W. C.

In: Applied Radiation and Isotopes, Vol. 49, No. 12, 01.12.1998, p. 1477-1479.

Research output: Contribution to journalArticle

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