Abstract
As part of the 2018 Immunotherapy Bridge congress (November 28-29, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on four topical clinical issues in immunotherapy today. These were: the relative importance of adaptive versus innate immunity in the anti-cancer immune response; the merits of combination versus sequential immunotherapy regimens in the treatment of cancer; the advantages and disadvantages of murine models of cancer versus humans in order to evaluate immunotherapy; and whether or not mechanisms of resistance to immunotherapy differ between different cancers. Discussion of these important topics are summarised in this report.
| Original language | English |
|---|---|
| Article number | 221 |
| Journal | Journal for ImmunoTherapy of Cancer |
| Volume | 7 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Aug 15 2019 |
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Keywords
- Anti-CTLA-4
- Anti-PD-1
- Cancer
- Combination therapy
- Immunity
- Immunotherapy
- Treatment resistance
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Molecular Medicine
- Oncology
- Pharmacology
- Cancer Research
Cite this
The great debate at "immunotherapy Bridge 2018", Naples, November 29th, 2018. / Ascierto, Paolo A.; Butterfield, Lisa H.; Demaria, Sandra; Ferris, Robert L.; Freeman, Gordon J.; Lo, Roger S.; Mantovani, Alberto; Nathan, Paul; Hamid, Omid; Politi, Katerina; Puzanov, Igor.
In: Journal for ImmunoTherapy of Cancer, Vol. 7, No. 1, 221, 15.08.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The great debate at "immunotherapy Bridge 2018", Naples, November 29th, 2018
AU - Ascierto, Paolo A.
AU - Butterfield, Lisa H.
AU - Demaria, Sandra
AU - Ferris, Robert L.
AU - Freeman, Gordon J.
AU - Lo, Roger S.
AU - Mantovani, Alberto
AU - Nathan, Paul
AU - Hamid, Omid
AU - Politi, Katerina
AU - Puzanov, Igor
PY - 2019/8/15
Y1 - 2019/8/15
N2 - As part of the 2018 Immunotherapy Bridge congress (November 28-29, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on four topical clinical issues in immunotherapy today. These were: the relative importance of adaptive versus innate immunity in the anti-cancer immune response; the merits of combination versus sequential immunotherapy regimens in the treatment of cancer; the advantages and disadvantages of murine models of cancer versus humans in order to evaluate immunotherapy; and whether or not mechanisms of resistance to immunotherapy differ between different cancers. Discussion of these important topics are summarised in this report.
AB - As part of the 2018 Immunotherapy Bridge congress (November 28-29, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on four topical clinical issues in immunotherapy today. These were: the relative importance of adaptive versus innate immunity in the anti-cancer immune response; the merits of combination versus sequential immunotherapy regimens in the treatment of cancer; the advantages and disadvantages of murine models of cancer versus humans in order to evaluate immunotherapy; and whether or not mechanisms of resistance to immunotherapy differ between different cancers. Discussion of these important topics are summarised in this report.
KW - Anti-CTLA-4
KW - Anti-PD-1
KW - Cancer
KW - Combination therapy
KW - Immunity
KW - Immunotherapy
KW - Treatment resistance
UR - http://www.scopus.com/inward/record.url?scp=85070958115&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070958115&partnerID=8YFLogxK
U2 - 10.1186/s40425-019-0683-0
DO - 10.1186/s40425-019-0683-0
M3 - Review article
AN - SCOPUS:85070958115
VL - 7
JO - Journal for ImmunoTherapy of Cancer
JF - Journal for ImmunoTherapy of Cancer
SN - 2051-1426
IS - 1
M1 - 221
ER -