The growing clinical importance of secondary tricuspid regurgitation

Maurizio Taramasso, Hugo Vanermen, Francesco Maisano, Andrea Guidotti, Giovanni La Canna, Ottavio Alfieri

Research output: Contribution to journalArticlepeer-review


Functional or secondary tricuspid regurgitation (STR) is the most frequent etiology of tricuspid valve pathology in Western countries. Surgical tricuspid repair has been avoided for years, because of the misconception that tricuspid regurgitation should disappear once the primary left-sided problem is treated; this results in a large number of untreated patients with STR. Over the past few years, many investigators have reported evidence in favor of a more aggressive surgical approach to STR. Consequently, interest has been growing in the physiopathology and treatment of STR. The purpose of this review is to explore the anatomical basis, pathophysiology, therapeutic approach, and future perspectives with regard to the management of STR.

Original languageEnglish
Pages (from-to)703-710
Number of pages8
JournalJournal of the American College of Cardiology
Issue number8
Publication statusPublished - Feb 21 2012


  • functional tricuspid regurgitation
  • tricuspid valve
  • valvular heart disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'The growing clinical importance of secondary tricuspid regurgitation'. Together they form a unique fingerprint.

Cite this