The haemodynamic response to the interictal epileptic spikes

Maria Gabriella Tana; Anna Maria Bianchi; Paolo Vitali; Flavio Villani; Sergio Cerutti

doi:10.1109/IEMBS.2007.4353519

The haemodynamic response to the interictal epileptic spikes

Maria Gabriella Tana, Anna Maria Bianchi, Paolo Vitali, Flavio Villani, Sergio Cerutti

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We studied the blood oxygen level dependent (BOLD) response to interictal epileptic spikes in a group of patients with focal epilepsy by simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). The detection of activated areas was performed by using an approach based on the theory of the General Linear Models (GLM). Since little is know about the haemodynamic response to the interictal epileptiform activity, for each region involved by fMRI response and for each subject we obtained a robust estimation of the haemodynamic response function (HRF) by using a Bayesian approach. We observed important variations in the time course of the haemodynamic response between patients and across the different fMRI areas of a same subject.

Original language	English
Title of host publication	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages	5223-5226
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2007.4353519
Publication status	Published - 2007
Event	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France Duration: Aug 23 2007 → Aug 26 2007

Other

Other	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Country	France
City	Lyon
Period	8/23/07 → 8/26/07

ASJC Scopus subject areas

Biomedical Engineering

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Tana, MG, Bianchi, AM, Vitali, P , Villani, F & Cerutti, S 2007, The haemodynamic response to the interictal epileptic spikes. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4353519, pp. 5223-5226, 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, France, 8/23/07. https://doi.org/10.1109/IEMBS.2007.4353519

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author = "Tana, {Maria Gabriella} and Bianchi, {Anna Maria} and Paolo Vitali and Flavio Villani and Sergio Cerutti",

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