The haemodynamic response to the interictal epileptic spikes

Maria Gabriella Tana, Anna Maria Bianchi, Paolo Vitali, Flavio Villani, Sergio Cerutti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We studied the blood oxygen level dependent (BOLD) response to interictal epileptic spikes in a group of patients with focal epilepsy by simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). The detection of activated areas was performed by using an approach based on the theory of the General Linear Models (GLM). Since little is know about the haemodynamic response to the interictal epileptiform activity, for each region involved by fMRI response and for each subject we obtained a robust estimation of the haemodynamic response function (HRF) by using a Bayesian approach. We observed important variations in the time course of the haemodynamic response between patients and across the different fMRI areas of a same subject.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages5223-5226
Number of pages4
DOIs
Publication statusPublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

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ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Tana, M. G., Bianchi, A. M., Vitali, P., Villani, F., & Cerutti, S. (2007). The haemodynamic response to the interictal epileptic spikes. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 5223-5226). [4353519] https://doi.org/10.1109/IEMBS.2007.4353519