The hbhA gene of Mycobacterium tuberculosis is specifically upregulated in the lungs but not in the spleens of aerogenically infected mice

Giovanni Delogu, Maurizio Sanguinetti, Brunella Posteraro, Stefano Rocca, Stefania Zanetti, Giovanni Fadda

Research output: Contribution to journalArticlepeer-review

Abstract

We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate from the site of primary infection.

Original languageEnglish
Pages (from-to)3006-3011
Number of pages6
JournalInfection and Immunity
Volume74
Issue number5
DOIs
Publication statusPublished - May 2006

ASJC Scopus subject areas

  • Immunology

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