TY - JOUR
T1 - The heart and shell. Anatomical and genetic similarities
AU - Versacci, Paolo
AU - Digilio, Maria Cristina
AU - Oliverio, Marco
AU - Dallapiccola, Bruno
AU - Marino, Bruno
PY - 2011/4
Y1 - 2011/4
N2 - Phenotypic resemblance does exist between normal and abnormal spiralization of great arteries in vertebrates and the spiral patterns of snail shells. The conserved Nodal gene is involved in the morphogenetic mechanism of these spiralizations in the great arteries of vertebrates and snail shells. These observationswiden the phylogenetic development horizon in humans20,21 and allowus to look at the harmonic heart anatomy from a new evolutionary perspective.
AB - Phenotypic resemblance does exist between normal and abnormal spiralization of great arteries in vertebrates and the spiral patterns of snail shells. The conserved Nodal gene is involved in the morphogenetic mechanism of these spiralizations in the great arteries of vertebrates and snail shells. These observationswiden the phylogenetic development horizon in humans20,21 and allowus to look at the harmonic heart anatomy from a new evolutionary perspective.
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UR - http://www.scopus.com/inward/citedby.url?scp=79953714866&partnerID=8YFLogxK
U2 - 10.1016/j.ahj.2010.12.023
DO - 10.1016/j.ahj.2010.12.023
M3 - Article
C2 - 21473961
AN - SCOPUS:79953714866
VL - 161
SP - 647
EP - 649
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 4
ER -