The hepatitis B virus X protein transactivation of c-fos and c-myc proto-oncogenes is mediated by multiple transcription factors.

M. L. Avantaggiati, C. Balsano, G. Natoli, E. De Marzio, H. Will, E. Elfassi, M. Levrero

Research output: Contribution to journalArticle


We have constructed two expression vectors in order to study the action of the HBV 17 Kd X protein on the c-fos and c-myc promoters. The results show that the promoters contain multiple elements that respond to X protein, suggesting involvement of multiple transcription factors. The exact mechanism of the interaction remains elusive, but our data allow speculation about the factors that may be influenced.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalArchives of virology. Supplementum
Publication statusPublished - 1992


ASJC Scopus subject areas

  • Immunology and Microbiology(all)

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