The histological and pathogenetic spectrum of cutaneous disease in monoclonal gammopathies

Franco Rongioletti, James W. Patterson, Alfredo Rebora

Research output: Contribution to journalArticlepeer-review

Abstract

The dermatological disorders associated with monoclonal gammopathies are clinically heterogeneous and may be divided into four groups with distinctive pathogenetic mechanisms (a) specific (infiltrative) disorders including primary and secondary cutaneous plasmacytoma and cutaneous lymphoplasmacytic infiltration of Waldenstrom's disease (b) skin disorders because of the deposition of monoclonal immunoglobulin (M protein), including amyloidoisis macroglobulinemia cutis, light chain deposition of Randall's disease, follicular spicules of the nose, and cryoglobulinemia (c) skin disorders associated with monoclonal gammopathies, including highly associated (>50%), weakly associated (

Original languageEnglish
Pages (from-to)705-721
Number of pages17
JournalJournal of Cutaneous Pathology
Volume35
Issue number8
DOIs
Publication statusPublished - Aug 2008

ASJC Scopus subject areas

  • Dermatology
  • Histology
  • Pathology and Forensic Medicine

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