The human pegivirus: A new name for an "ancient" virus. Can transfusion medicine come up with something new?

G. Marano; M. Franchini; B. Farina; V. Piccinini; S. Pupella; S. Vaglio; G. Grazzini; G. M. Liumbruno

doi:10.4149/av_2017_402

The human pegivirus: A new name for an "ancient" virus. Can transfusion medicine come up with something new?

G. Marano, M. Franchini, B. Farina, V. Piccinini, S. Pupella, S. Vaglio, G. Grazzini, G. M. Liumbruno

Istituto Superiore di Sanita'

Research output: Contribution to journal › Review article › peer-review

Abstract

Human pegivirus (HPgV, formerly called GB virus C/hepatitis G virus) is a poorly understood RNA virus of the Flaviviridae family. The HPgV infection is common worldwide and the virus is likely transmitted by blood products. At this time, no causal association between HPgV and human diseases has been identified. While waiting for new findings to better understand the Pegivirus genus, the aim of our narrative review is to discuss the currently available information on HPgV focusing on its prevalence in blood donors and its potential threat to transfusion safety.

Original language	English
Pages (from-to)	401-412
Number of pages	12
Journal	Acta Virologica
Volume	61
Issue number	4
DOIs	https://doi.org/10.4149/av_2017_402
Publication status	Published - Jan 1 2017

Keywords

Blood transfusion
Flaviviridae
GB virus type C
Hepatitis
Hepatitis G virus
Human pegivirus

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.4149/av_2017_402

Cite this

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AU - Piccinini, V.

AU - Pupella, S.

AU - Vaglio, S.

AU - Grazzini, G.

AU - Liumbruno, G. M.

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AB - Human pegivirus (HPgV, formerly called GB virus C/hepatitis G virus) is a poorly understood RNA virus of the Flaviviridae family. The HPgV infection is common worldwide and the virus is likely transmitted by blood products. At this time, no causal association between HPgV and human diseases has been identified. While waiting for new findings to better understand the Pegivirus genus, the aim of our narrative review is to discuss the currently available information on HPgV focusing on its prevalence in blood donors and its potential threat to transfusion safety.

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The human pegivirus: A new name for an "ancient" virus. Can transfusion medicine come up with something new?

Abstract

Keywords

ASJC Scopus subject areas

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