The human pegivirus: A new name for an "ancient" virus. Can transfusion medicine come up with something new?

G. Marano, M. Franchini, B. Farina, V. Piccinini, S. Pupella, S. Vaglio, G. Grazzini, G. M. Liumbruno

Research output: Contribution to journalReview article

Abstract

Human pegivirus (HPgV, formerly called GB virus C/hepatitis G virus) is a poorly understood RNA virus of the Flaviviridae family. The HPgV infection is common worldwide and the virus is likely transmitted by blood products. At this time, no causal association between HPgV and human diseases has been identified. While waiting for new findings to better understand the Pegivirus genus, the aim of our narrative review is to discuss the currently available information on HPgV focusing on its prevalence in blood donors and its potential threat to transfusion safety.

Original languageEnglish
Pages (from-to)401-412
Number of pages12
JournalActa Virologica
Volume61
Issue number4
DOIs
Publication statusPublished - Jan 1 2017

Keywords

  • Blood transfusion
  • Flaviviridae
  • GB virus type C
  • Hepatitis
  • Hepatitis G virus
  • Human pegivirus

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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