The Hydroxylation of tryptophan in vivo by brain

S. Consolo, S. Garattini, R. Ghielmetti, P. Morselli, L. Valzelli

Research output: Contribution to journalArticle


Tryptophan injected intracerebrally in rats increases the level of brain serotonin. This increase occurs also in animals pretreated with reserpine or with a monoamineoxidase inhibitor. Other studies show that tryptophan, tryptamine or 6-hydroxytryptamine are not interfering in the determination of brain serotonin.

Original languageEnglish
Pages (from-to)625-630
Number of pages6
JournalLife Sciences
Issue number5
Publication statusPublished - Mar 1965

ASJC Scopus subject areas

  • Pharmacology

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    Consolo, S., Garattini, S., Ghielmetti, R., Morselli, P., & Valzelli, L. (1965). The Hydroxylation of tryptophan in vivo by brain. Life Sciences, 4(5), 625-630.