In conclusion, the hyper IgE syndrome is an exciting 'experiment of Nature' which demonstrates the relationship between severe allergy, immunological dysfunctions and recurrent infections. Several experimental data suggest that histamine inhibits cellular chemotaxis and T lymphocyte functions. The effectiveness of Levamisole in some cases may lend some support to this hypothesis, but further research is needed to define more exactly the role of histamine as a modulator of the inflammatory response.
|Number of pages||6|
|Journal||Allergologia et Immunopathologia|
|Publication status||Published - 1979|
ASJC Scopus subject areas
- Immunology and Allergy