Abstract
The hypophysis-thyroid function in perinatal age was studied by assaying TSH and thyroid hormones (T 3, T 4) in: the cord blood of 1792 newborns of four gestational age groups (27-32 weeks, 33-34, 35-36, 37-42); and the venous blood at the fifth day of life in 72 term newborns. TSH levels decrease and T 4-T 3 levels increase significantly from the 27th to 35-36 wk of gestational age. There is a further significant increase of T 4 after 35-36 wk. There are no differences in cord blood hormone levels between small and large for date newborns. TSH level in cord blood depends on the type of delivery; it is higher in babies with fetal-neonatal distress, lower in those born by caesarean section, intermediate in newborns born physiologically. No differences were observed in TSH levels between breast fed newborns and those on cow's milk based formulas. The increase of thyroid hormone levels along with the gestational age parallels that of the lecithin/sphingomyelin ratio in the amniotic fluid. A significant correlation exists between this ratio and T 4 levels after the gestational age of 35-36 wk. The hypothesis of a role of thyroid hormone in the treatment of the neonatal respiratory distress syndrome is discussed.
| Original language | Italian |
|---|---|
| Pages (from-to) | 587-593 |
| Number of pages | 7 |
| Journal | Rivista Italiana di Pediatria |
| Volume | 6 |
| Issue number | 5 |
| Publication status | Published - 1980 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
LA FUNZIONE IPOFISO-TIROIDEA IN ETA PERINATALE. / Tecilazich, D.; Tonini, G.; Mangiarotti, M. A.
In: Rivista Italiana di Pediatria, Vol. 6, No. 5, 1980, p. 587-593.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - LA FUNZIONE IPOFISO-TIROIDEA IN ETA PERINATALE
AU - Tecilazich, D.
AU - Tonini, G.
AU - Mangiarotti, M. A.
PY - 1980
Y1 - 1980
N2 - The hypophysis-thyroid function in perinatal age was studied by assaying TSH and thyroid hormones (T 3, T 4) in: the cord blood of 1792 newborns of four gestational age groups (27-32 weeks, 33-34, 35-36, 37-42); and the venous blood at the fifth day of life in 72 term newborns. TSH levels decrease and T 4-T 3 levels increase significantly from the 27th to 35-36 wk of gestational age. There is a further significant increase of T 4 after 35-36 wk. There are no differences in cord blood hormone levels between small and large for date newborns. TSH level in cord blood depends on the type of delivery; it is higher in babies with fetal-neonatal distress, lower in those born by caesarean section, intermediate in newborns born physiologically. No differences were observed in TSH levels between breast fed newborns and those on cow's milk based formulas. The increase of thyroid hormone levels along with the gestational age parallels that of the lecithin/sphingomyelin ratio in the amniotic fluid. A significant correlation exists between this ratio and T 4 levels after the gestational age of 35-36 wk. The hypothesis of a role of thyroid hormone in the treatment of the neonatal respiratory distress syndrome is discussed.
AB - The hypophysis-thyroid function in perinatal age was studied by assaying TSH and thyroid hormones (T 3, T 4) in: the cord blood of 1792 newborns of four gestational age groups (27-32 weeks, 33-34, 35-36, 37-42); and the venous blood at the fifth day of life in 72 term newborns. TSH levels decrease and T 4-T 3 levels increase significantly from the 27th to 35-36 wk of gestational age. There is a further significant increase of T 4 after 35-36 wk. There are no differences in cord blood hormone levels between small and large for date newborns. TSH level in cord blood depends on the type of delivery; it is higher in babies with fetal-neonatal distress, lower in those born by caesarean section, intermediate in newborns born physiologically. No differences were observed in TSH levels between breast fed newborns and those on cow's milk based formulas. The increase of thyroid hormone levels along with the gestational age parallels that of the lecithin/sphingomyelin ratio in the amniotic fluid. A significant correlation exists between this ratio and T 4 levels after the gestational age of 35-36 wk. The hypothesis of a role of thyroid hormone in the treatment of the neonatal respiratory distress syndrome is discussed.
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M3 - Articolo
AN - SCOPUS:0019255084
VL - 6
SP - 587
EP - 593
JO - Rivista Italiana di Pediatria
JF - Rivista Italiana di Pediatria
SN - 0392-5161
IS - 5
ER -