The immunology of exceptional individuals: the lesson of centenarians

Claudio Franceschi, Daniela Monti, Paolo Sansoni, Andrea Cossarizza

Research output: Contribution to journalArticlepeer-review


Centenarians are the best example of successful ageing, since they have escaped the major age-associated diseases, and most are in good mental and physical condition. Here, Claudio Franceschi and colleagues discuss how the study of their immune systems reveals that several immune parameters are well conserved, suggesting that a complex remodelling of most immune parameters occurs with age, rather than a unidirectional deterioration.

Original languageEnglish
Pages (from-to)12-16
Number of pages5
JournalImmunology Today
Issue number1
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Immunology


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