The impact of adolescent stress experiences on neurobiological development

Luisa Lo lacono, Valeria Carola

Research output: Contribution to journalArticlepeer-review


Adolescence is considered a developmental period of heightened vulnerability to many psychological dysfunctions-primarily due to the high structural neuronal plasticity that accompanies the associated physical and cognitive gains, rendering an individual highly susceptible to environmental stressors during this time.Recently, interest has been generated in the study of neuronal and behavioral adaptation to adverse experiences during adolescence. This review will provide an overview of the principal neurobehavioral changes that occur during adolescence and describe what happens when the maturation of these functions is altered by stressful environmental stimuli.

Original languageEnglish
JournalSeminars in Cell and Developmental Biology
Publication statusAccepted/In press - Jan 1 2017


  • Adolescence
  • Amygdala
  • Brain
  • Early-life stress
  • Frontal cortex
  • HPA axis
  • Human
  • Mouse

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology


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