The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology

Antonio Passaro, Patrizia Trenta, Davide Conte, Giuseppe Campennì, Angelina De Benedetto, Enrico Cortesi

Research output: Contribution to journalArticle

Abstract

Non-small-cell lung cancer remains the leading cause of cancer-related mortality in the United States and Europe. Most patients are diagnosed with metastatic disease for which chemotherapy remains the cornerstone of treatment. In non-metastatic disease, surgery is the most potentially curative therapeutic option, but its outcome is still poor, in particular for patients with lymph node involvement. Therefore, several randomized adjuvant/neoadjuvant trials using chemotherapy and/or radiotherapy investigated the possibility of increasing the overall survival of patients with surgically treated lung cancer. The findings are reviewed in this article.

Original languageEnglish
Pages (from-to)243-249
Number of pages7
JournalThoracic Surgery Clinics
Volume22
Issue number2
DOIs
Publication statusPublished - May 2012

Fingerprint

Lymphatic System
Thorax
Drug Therapy
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Radiotherapy
Lymph Nodes
Survival
Mortality
Therapeutics
Neoplasms

Keywords

  • Adjuvant chemotherapy
  • Lymph node
  • Neoadjuvant chemotherapy
  • Non-small cell lung cancer

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology. / Passaro, Antonio; Trenta, Patrizia; Conte, Davide; Campennì, Giuseppe; De Benedetto, Angelina; Cortesi, Enrico.

In: Thoracic Surgery Clinics, Vol. 22, No. 2, 05.2012, p. 243-249.

Research output: Contribution to journalArticle

Passaro, A, Trenta, P, Conte, D, Campennì, G, De Benedetto, A & Cortesi, E 2012, 'The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology', Thoracic Surgery Clinics, vol. 22, no. 2, pp. 243-249. https://doi.org/10.1016/j.thorsurg.2011.11.002
Passaro, Antonio ; Trenta, Patrizia ; Conte, Davide ; Campennì, Giuseppe ; De Benedetto, Angelina ; Cortesi, Enrico. / The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology. In: Thoracic Surgery Clinics. 2012 ; Vol. 22, No. 2. pp. 243-249.
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