The impact of different left ventricular geometric patterns on right ventricular deformation and function in hypertensive patients

Marijana Tadic, Cesare Cuspidi, Vladan Vukomanovic, Vesna Kocijancic, Vera Celic

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Right ventricular (RV) hypertrophy and RV systolic dysfunction are predictors of poor outcome. No study has investigated RV deformation and function in hypertensive patients with different left ventricular (LV) geometry patterns.

AIM: To investigate RV deformation and function in hypertensive patients with different LV geometric patterns, by using two-dimensional (2D) strain analysis and three-dimensional (3D) echocardiography.

METHODS: This cross-sectional study included 184 hypertensive subjects, all of whom underwent complete 2D and 3D examinations. The participants were separated into two groups (with and without LV hypertrophy [LVH]), and were then divided into four further groups according to different LV geometry patterns: normal LV geometry, concentric remodelling, eccentric LVH and concentric LVH.

RESULTS: Patients with LVH had significantly higher RV end-diastolic and end-systolic volume indexes and stroke volumes than those without LVH. Conversely, 3D RV ejection fraction was lower among subjects with LVH. 3D RV volume indexes gradually increased from subjects with normal LV geometry to those with concentric LVH, whereas 3D RV ejection fraction progressively decreased in the same direction. Global RV longitudinal strain was significantly lower in LVH subjects than in patients without LVH. 2D RV mechanics progressively deteriorated from patients with normal LV geometry to those with concentric LVH. Eccentric and concentric LVH were associated with reduced longitudinal lateral wall RV strain and early diastolic strain rate.

CONCLUSIONS: 2D RV myocardial deformation and 3D RV function are affected significantly by LV geometry in hypertensive patients. Concentric and eccentric LVH patterns have the greatest unfavourable effect on RV deformation.

Original languageEnglish
Pages (from-to)311-20
Number of pages10
JournalArchives of Cardiovascular Diseases
Volume109
Issue number5
DOIs
Publication statusPublished - May 2016

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Right Ventricular Function
Hypertrophy
Stroke Volume
Three-Dimensional Echocardiography
Right Ventricular Dysfunction
Right Ventricular Hypertrophy
Left Ventricular Hypertrophy
Mechanics
Cross-Sectional Studies

Keywords

  • Cross-Sectional Studies
  • Echocardiography
  • Electrocardiography
  • Female
  • Heart Ventricles
  • Humans
  • Hypertension
  • Hypertrophy, Left Ventricular
  • Male
  • Middle Aged
  • Stroke Volume
  • Ventricular Function, Right
  • Journal Article

Cite this

The impact of different left ventricular geometric patterns on right ventricular deformation and function in hypertensive patients. / Tadic, Marijana; Cuspidi, Cesare; Vukomanovic, Vladan; Kocijancic, Vesna; Celic, Vera.

In: Archives of Cardiovascular Diseases, Vol. 109, No. 5, 05.2016, p. 311-20.

Research output: Contribution to journalArticle

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abstract = "BACKGROUND: Right ventricular (RV) hypertrophy and RV systolic dysfunction are predictors of poor outcome. No study has investigated RV deformation and function in hypertensive patients with different left ventricular (LV) geometry patterns.AIM: To investigate RV deformation and function in hypertensive patients with different LV geometric patterns, by using two-dimensional (2D) strain analysis and three-dimensional (3D) echocardiography.METHODS: This cross-sectional study included 184 hypertensive subjects, all of whom underwent complete 2D and 3D examinations. The participants were separated into two groups (with and without LV hypertrophy [LVH]), and were then divided into four further groups according to different LV geometry patterns: normal LV geometry, concentric remodelling, eccentric LVH and concentric LVH.RESULTS: Patients with LVH had significantly higher RV end-diastolic and end-systolic volume indexes and stroke volumes than those without LVH. Conversely, 3D RV ejection fraction was lower among subjects with LVH. 3D RV volume indexes gradually increased from subjects with normal LV geometry to those with concentric LVH, whereas 3D RV ejection fraction progressively decreased in the same direction. Global RV longitudinal strain was significantly lower in LVH subjects than in patients without LVH. 2D RV mechanics progressively deteriorated from patients with normal LV geometry to those with concentric LVH. Eccentric and concentric LVH were associated with reduced longitudinal lateral wall RV strain and early diastolic strain rate.CONCLUSIONS: 2D RV myocardial deformation and 3D RV function are affected significantly by LV geometry in hypertensive patients. Concentric and eccentric LVH patterns have the greatest unfavourable effect on RV deformation.",
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T1 - The impact of different left ventricular geometric patterns on right ventricular deformation and function in hypertensive patients

AU - Tadic, Marijana

AU - Cuspidi, Cesare

AU - Vukomanovic, Vladan

AU - Kocijancic, Vesna

AU - Celic, Vera

N1 - Copyright © 2016 Elsevier Masson SAS. All rights reserved.

PY - 2016/5

Y1 - 2016/5

N2 - BACKGROUND: Right ventricular (RV) hypertrophy and RV systolic dysfunction are predictors of poor outcome. No study has investigated RV deformation and function in hypertensive patients with different left ventricular (LV) geometry patterns.AIM: To investigate RV deformation and function in hypertensive patients with different LV geometric patterns, by using two-dimensional (2D) strain analysis and three-dimensional (3D) echocardiography.METHODS: This cross-sectional study included 184 hypertensive subjects, all of whom underwent complete 2D and 3D examinations. The participants were separated into two groups (with and without LV hypertrophy [LVH]), and were then divided into four further groups according to different LV geometry patterns: normal LV geometry, concentric remodelling, eccentric LVH and concentric LVH.RESULTS: Patients with LVH had significantly higher RV end-diastolic and end-systolic volume indexes and stroke volumes than those without LVH. Conversely, 3D RV ejection fraction was lower among subjects with LVH. 3D RV volume indexes gradually increased from subjects with normal LV geometry to those with concentric LVH, whereas 3D RV ejection fraction progressively decreased in the same direction. Global RV longitudinal strain was significantly lower in LVH subjects than in patients without LVH. 2D RV mechanics progressively deteriorated from patients with normal LV geometry to those with concentric LVH. Eccentric and concentric LVH were associated with reduced longitudinal lateral wall RV strain and early diastolic strain rate.CONCLUSIONS: 2D RV myocardial deformation and 3D RV function are affected significantly by LV geometry in hypertensive patients. Concentric and eccentric LVH patterns have the greatest unfavourable effect on RV deformation.

AB - BACKGROUND: Right ventricular (RV) hypertrophy and RV systolic dysfunction are predictors of poor outcome. No study has investigated RV deformation and function in hypertensive patients with different left ventricular (LV) geometry patterns.AIM: To investigate RV deformation and function in hypertensive patients with different LV geometric patterns, by using two-dimensional (2D) strain analysis and three-dimensional (3D) echocardiography.METHODS: This cross-sectional study included 184 hypertensive subjects, all of whom underwent complete 2D and 3D examinations. The participants were separated into two groups (with and without LV hypertrophy [LVH]), and were then divided into four further groups according to different LV geometry patterns: normal LV geometry, concentric remodelling, eccentric LVH and concentric LVH.RESULTS: Patients with LVH had significantly higher RV end-diastolic and end-systolic volume indexes and stroke volumes than those without LVH. Conversely, 3D RV ejection fraction was lower among subjects with LVH. 3D RV volume indexes gradually increased from subjects with normal LV geometry to those with concentric LVH, whereas 3D RV ejection fraction progressively decreased in the same direction. Global RV longitudinal strain was significantly lower in LVH subjects than in patients without LVH. 2D RV mechanics progressively deteriorated from patients with normal LV geometry to those with concentric LVH. Eccentric and concentric LVH were associated with reduced longitudinal lateral wall RV strain and early diastolic strain rate.CONCLUSIONS: 2D RV myocardial deformation and 3D RV function are affected significantly by LV geometry in hypertensive patients. Concentric and eccentric LVH patterns have the greatest unfavourable effect on RV deformation.

KW - Cross-Sectional Studies

KW - Echocardiography

KW - Electrocardiography

KW - Female

KW - Heart Ventricles

KW - Humans

KW - Hypertension

KW - Hypertrophy, Left Ventricular

KW - Male

KW - Middle Aged

KW - Stroke Volume

KW - Ventricular Function, Right

KW - Journal Article

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DO - 10.1016/j.acvd.2015.12.006

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C2 - 27020514

VL - 109

SP - 311

EP - 320

JO - Archives of Cardiovascular Diseases

JF - Archives of Cardiovascular Diseases

SN - 1875-2136

IS - 5

ER -