The impact of malnutrition on quality of life in patients with systemic sclerosis

Emelina Preis, Kristina Franz, Elise Siegert, Alexander Makowka, Christine March, Gabriela Riemekasten, Emanuele Cereda, Kristina Norman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background/objectives: Our objective was to investigate the prevalence of malnutrition in patients with systemic sclerosis (SSc) and its impact on their quality of life (QoL). Subjects/methods: One hundred and twenty-nine patients with SSc underwent clinical evaluation and were screened with the Malnutrition Universal Screening Tool (MUST). Malnutrition was defined as MUST score ≥2.To investigate QoL, all patients completed the Short Form 36 Questionnaire and the Scleroderma Health Assessment Questionnaire. The data were analyzed with IBM SPSS® Statistics by using χ 2/Fisher's test, Mann-Whitney U test, correlation, and linear regression analysis. Results: One hundred and twenty-nine patients were included in this study (mean age was 59.1 ± 13.8 years, 90.7% women). The prevalence of malnutrition was 10.9%. Age and disease duration were not significantly different between malnourished and well-nourished patients. All QoL scores (except bodily pain and self-reported health) were significantly impaired in malnourished patients. Furthermore, the Scleroderma Health Assessment Score score which assesses disease-specific QoL was significantly higher in the malnourished patients (1.6 ± 0.73 compared to 0.91 ± 0.61 in well-nourished patients; p = 0.001), reflecting a lower QoL due to disease-specific impairments. Conclusions: Severe malnutrition in SSc patients is associated with reduced QoL. Standardized nutritional screening should routinely be conducted to identify the risk of malnutrition in order to enable an intervention with multimodal treatment and avoid the serious consequences associated with severe malnutrition.

Original languageEnglish
Pages (from-to)504-510
Number of pages7
JournalEuropean Journal of Clinical Nutrition
Volume72
Issue number4
DOIs
Publication statusPublished - Apr 1 2018

Fingerprint

Systemic Scleroderma
Malnutrition
Quality of Life
Health
Combined Modality Therapy
Nonparametric Statistics
Linear Models
Regression Analysis
Pain

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Preis, E., Franz, K., Siegert, E., Makowka, A., March, C., Riemekasten, G., ... Norman, K. (2018). The impact of malnutrition on quality of life in patients with systemic sclerosis. European Journal of Clinical Nutrition, 72(4), 504-510. https://doi.org/10.1038/s41430-018-0116-z

The impact of malnutrition on quality of life in patients with systemic sclerosis. / Preis, Emelina; Franz, Kristina; Siegert, Elise; Makowka, Alexander; March, Christine; Riemekasten, Gabriela; Cereda, Emanuele; Norman, Kristina.

In: European Journal of Clinical Nutrition, Vol. 72, No. 4, 01.04.2018, p. 504-510.

Research output: Contribution to journalArticle

Preis, E, Franz, K, Siegert, E, Makowka, A, March, C, Riemekasten, G, Cereda, E & Norman, K 2018, 'The impact of malnutrition on quality of life in patients with systemic sclerosis', European Journal of Clinical Nutrition, vol. 72, no. 4, pp. 504-510. https://doi.org/10.1038/s41430-018-0116-z
Preis, Emelina ; Franz, Kristina ; Siegert, Elise ; Makowka, Alexander ; March, Christine ; Riemekasten, Gabriela ; Cereda, Emanuele ; Norman, Kristina. / The impact of malnutrition on quality of life in patients with systemic sclerosis. In: European Journal of Clinical Nutrition. 2018 ; Vol. 72, No. 4. pp. 504-510.
@article{2485910e393c44ca8e8253e460e74f68,
title = "The impact of malnutrition on quality of life in patients with systemic sclerosis",
abstract = "Background/objectives: Our objective was to investigate the prevalence of malnutrition in patients with systemic sclerosis (SSc) and its impact on their quality of life (QoL). Subjects/methods: One hundred and twenty-nine patients with SSc underwent clinical evaluation and were screened with the Malnutrition Universal Screening Tool (MUST). Malnutrition was defined as MUST score ≥2.To investigate QoL, all patients completed the Short Form 36 Questionnaire and the Scleroderma Health Assessment Questionnaire. The data were analyzed with IBM SPSS{\circledR} Statistics by using χ 2/Fisher's test, Mann-Whitney U test, correlation, and linear regression analysis. Results: One hundred and twenty-nine patients were included in this study (mean age was 59.1 ± 13.8 years, 90.7{\%} women). The prevalence of malnutrition was 10.9{\%}. Age and disease duration were not significantly different between malnourished and well-nourished patients. All QoL scores (except bodily pain and self-reported health) were significantly impaired in malnourished patients. Furthermore, the Scleroderma Health Assessment Score score which assesses disease-specific QoL was significantly higher in the malnourished patients (1.6 ± 0.73 compared to 0.91 ± 0.61 in well-nourished patients; p = 0.001), reflecting a lower QoL due to disease-specific impairments. Conclusions: Severe malnutrition in SSc patients is associated with reduced QoL. Standardized nutritional screening should routinely be conducted to identify the risk of malnutrition in order to enable an intervention with multimodal treatment and avoid the serious consequences associated with severe malnutrition.",
author = "Emelina Preis and Kristina Franz and Elise Siegert and Alexander Makowka and Christine March and Gabriela Riemekasten and Emanuele Cereda and Kristina Norman",
year = "2018",
month = "4",
day = "1",
doi = "10.1038/s41430-018-0116-z",
language = "English",
volume = "72",
pages = "504--510",
journal = "European Journal of Clinical Nutrition",
issn = "0954-3007",
publisher = "Nature Publishing Group",
number = "4",

}

TY - JOUR

T1 - The impact of malnutrition on quality of life in patients with systemic sclerosis

AU - Preis, Emelina

AU - Franz, Kristina

AU - Siegert, Elise

AU - Makowka, Alexander

AU - March, Christine

AU - Riemekasten, Gabriela

AU - Cereda, Emanuele

AU - Norman, Kristina

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Background/objectives: Our objective was to investigate the prevalence of malnutrition in patients with systemic sclerosis (SSc) and its impact on their quality of life (QoL). Subjects/methods: One hundred and twenty-nine patients with SSc underwent clinical evaluation and were screened with the Malnutrition Universal Screening Tool (MUST). Malnutrition was defined as MUST score ≥2.To investigate QoL, all patients completed the Short Form 36 Questionnaire and the Scleroderma Health Assessment Questionnaire. The data were analyzed with IBM SPSS® Statistics by using χ 2/Fisher's test, Mann-Whitney U test, correlation, and linear regression analysis. Results: One hundred and twenty-nine patients were included in this study (mean age was 59.1 ± 13.8 years, 90.7% women). The prevalence of malnutrition was 10.9%. Age and disease duration were not significantly different between malnourished and well-nourished patients. All QoL scores (except bodily pain and self-reported health) were significantly impaired in malnourished patients. Furthermore, the Scleroderma Health Assessment Score score which assesses disease-specific QoL was significantly higher in the malnourished patients (1.6 ± 0.73 compared to 0.91 ± 0.61 in well-nourished patients; p = 0.001), reflecting a lower QoL due to disease-specific impairments. Conclusions: Severe malnutrition in SSc patients is associated with reduced QoL. Standardized nutritional screening should routinely be conducted to identify the risk of malnutrition in order to enable an intervention with multimodal treatment and avoid the serious consequences associated with severe malnutrition.

AB - Background/objectives: Our objective was to investigate the prevalence of malnutrition in patients with systemic sclerosis (SSc) and its impact on their quality of life (QoL). Subjects/methods: One hundred and twenty-nine patients with SSc underwent clinical evaluation and were screened with the Malnutrition Universal Screening Tool (MUST). Malnutrition was defined as MUST score ≥2.To investigate QoL, all patients completed the Short Form 36 Questionnaire and the Scleroderma Health Assessment Questionnaire. The data were analyzed with IBM SPSS® Statistics by using χ 2/Fisher's test, Mann-Whitney U test, correlation, and linear regression analysis. Results: One hundred and twenty-nine patients were included in this study (mean age was 59.1 ± 13.8 years, 90.7% women). The prevalence of malnutrition was 10.9%. Age and disease duration were not significantly different between malnourished and well-nourished patients. All QoL scores (except bodily pain and self-reported health) were significantly impaired in malnourished patients. Furthermore, the Scleroderma Health Assessment Score score which assesses disease-specific QoL was significantly higher in the malnourished patients (1.6 ± 0.73 compared to 0.91 ± 0.61 in well-nourished patients; p = 0.001), reflecting a lower QoL due to disease-specific impairments. Conclusions: Severe malnutrition in SSc patients is associated with reduced QoL. Standardized nutritional screening should routinely be conducted to identify the risk of malnutrition in order to enable an intervention with multimodal treatment and avoid the serious consequences associated with severe malnutrition.

UR - http://www.scopus.com/inward/record.url?scp=85043319801&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043319801&partnerID=8YFLogxK

U2 - 10.1038/s41430-018-0116-z

DO - 10.1038/s41430-018-0116-z

M3 - Article

AN - SCOPUS:85043319801

VL - 72

SP - 504

EP - 510

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

IS - 4

ER -