The impact of oral contraception on vulvovaginal candidiasis

Arsenio Spinillo, Ezio Capuzzo, Sabrina Nicola, Federica Baltaro, Antonella Ferrari, Antonio Monaco

Research output: Contribution to journalArticlepeer-review


To evaluate risk factors related to sociodemographic and clinical variables, oral contraception and sexual behavior of women with recurrent vulvovaginal candidiasis, we conducted a case-control study comparing 153 patients with recurrent vulvovaginal candidiasis with both asymptomatic women with negative vaginal cultures and patients with nonrecurrent symptomatic vulvovaginal candidiasis. In logistic regression analysis, patients with recurrent Candida vaginitis were more likely than negative controls to have used any contraceptive method in the year before evaluation, to have used antibiotics in the month preceding the visit, and to have a higher number of lifetime sex partners. Compared to patients with nonrecurrent Candida vaginitis, patients with recurrent infection were more likely to use oral contraception and to have a higher frequency of monthly intercourse. The proportion of recur rent disease attributable to the pill averages 11-12%. We conclude that oral contraceptives may influence the recurrence of symptomatic vulvovaginal candidiasis.

Original languageEnglish
Pages (from-to)293-297
Number of pages5
Issue number5
Publication statusPublished - 1995


  • oral contraceptives
  • recurrent
  • sexual activity
  • vulvovaginal candidiasis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine
  • Medicine(all)


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