Importanza e limiti dei test di laboratorio per valutare il passaggio transplacentare di emazie fetali nel circolo materno.

Translated title of the contribution: The importance and limits of laboratory tests for evaluating the transplacental passage of fetal erythrocytes into the maternal circulation

R. Levi D'Ancona, G. Ricci, S. Alberico, R. Pregazzi, G. Maso, G. L. Molaro

Research output: Contribution to journalArticle

Abstract

The KBB acid elution test is used to assess the presence and extent of transplacental passage of fetal cells into the maternal circulation both as a diagnostic aid in detecting hemorrhage before birth and in monitoring pregnancies at risk for hemolytic disease of the newborn. However the technique is ineffective when an hereditary Hb-pathy with associated increase in HbF is present in the mother, like the HPFH, delta-beta thalassemia and other hereditary abnormal hemoglobins. A mother with HPFH and another mother with delta-beta thalassemia with false positive result of the acid-elution test are described and the need for an extension of the clinical and laboratory study in families with hereditary HbF disorder is stressed.

Translated title of the contributionThe importance and limits of laboratory tests for evaluating the transplacental passage of fetal erythrocytes into the maternal circulation
Original languageItalian
Pages (from-to)391-394
Number of pages4
JournalMinerva Ginecologica
Volume45
Issue number9
Publication statusPublished - Sep 1993

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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