Abstract
Background Left ventricular hypertrophy (LVH) is a risk factor for all-cause mortality. Left ventricular (LV) mass is usually indexed for normalizing the value to the patients phenotype and a correction by body surface area (BSA) is widely utilized being the only approved one according to the last echocardiography guidelines. However indexing LV mass by BSA may cause an underestimation of LVH prevalence in obese subjects and many authors have utilized in the obese subset of patients a correction by height2.7. The aim of our study was to quantify the number of obese patients who, despite having an increased LV mass, fall in the range of normality because they do not reach the LVH cutoff according to the new guidelines. Methods We reviewed the echocardiograms of 384 white women free from cardiovascular disease. Ninety-six patients (25%) were obese: among them 42 had mild obesity and 54 had moderate or severe obesity. Results In the obese group, the prevalence of LVH using the absolute LV mass value was similar to the one obtained with the height2.7 correction while a significant smaller number of patients had LVH according to BSA correction. Our study confirms that the method used for correcting LV mass significantly influences the diagnosis of LVH in a non-selected female population: using body surface area underestimates the prevalence of LVH as compared to allometric measures in the obese subset of patients. Conclusion We recommend that height2.7 be used for LV mass correction in obese patients.
| Original language | English |
|---|---|
| Pages (from-to) | 404-406 |
| Number of pages | 3 |
| Journal | International Journal of Cardiology |
| Volume | 227 |
| DOIs | |
| Publication status | Published - Jan 15 2017 |
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Keywords
- Echocardiography
- Left ventricular hypertrophy
- Obesity
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The importance of a shared definition of left ventricular hypertrophy : The case of obese women. / Alessandro Gondoni, Luca; Titon, Anna Maria; Montano, Mariella; Nibbio, Ferruccio; Bertone, Gianandrea.
In: International Journal of Cardiology, Vol. 227, 15.01.2017, p. 404-406.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The importance of a shared definition of left ventricular hypertrophy
T2 - The case of obese women
AU - Alessandro Gondoni, Luca
AU - Titon, Anna Maria
AU - Montano, Mariella
AU - Nibbio, Ferruccio
AU - Bertone, Gianandrea
PY - 2017/1/15
Y1 - 2017/1/15
N2 - Background Left ventricular hypertrophy (LVH) is a risk factor for all-cause mortality. Left ventricular (LV) mass is usually indexed for normalizing the value to the patients phenotype and a correction by body surface area (BSA) is widely utilized being the only approved one according to the last echocardiography guidelines. However indexing LV mass by BSA may cause an underestimation of LVH prevalence in obese subjects and many authors have utilized in the obese subset of patients a correction by height2.7. The aim of our study was to quantify the number of obese patients who, despite having an increased LV mass, fall in the range of normality because they do not reach the LVH cutoff according to the new guidelines. Methods We reviewed the echocardiograms of 384 white women free from cardiovascular disease. Ninety-six patients (25%) were obese: among them 42 had mild obesity and 54 had moderate or severe obesity. Results In the obese group, the prevalence of LVH using the absolute LV mass value was similar to the one obtained with the height2.7 correction while a significant smaller number of patients had LVH according to BSA correction. Our study confirms that the method used for correcting LV mass significantly influences the diagnosis of LVH in a non-selected female population: using body surface area underestimates the prevalence of LVH as compared to allometric measures in the obese subset of patients. Conclusion We recommend that height2.7 be used for LV mass correction in obese patients.
AB - Background Left ventricular hypertrophy (LVH) is a risk factor for all-cause mortality. Left ventricular (LV) mass is usually indexed for normalizing the value to the patients phenotype and a correction by body surface area (BSA) is widely utilized being the only approved one according to the last echocardiography guidelines. However indexing LV mass by BSA may cause an underestimation of LVH prevalence in obese subjects and many authors have utilized in the obese subset of patients a correction by height2.7. The aim of our study was to quantify the number of obese patients who, despite having an increased LV mass, fall in the range of normality because they do not reach the LVH cutoff according to the new guidelines. Methods We reviewed the echocardiograms of 384 white women free from cardiovascular disease. Ninety-six patients (25%) were obese: among them 42 had mild obesity and 54 had moderate or severe obesity. Results In the obese group, the prevalence of LVH using the absolute LV mass value was similar to the one obtained with the height2.7 correction while a significant smaller number of patients had LVH according to BSA correction. Our study confirms that the method used for correcting LV mass significantly influences the diagnosis of LVH in a non-selected female population: using body surface area underestimates the prevalence of LVH as compared to allometric measures in the obese subset of patients. Conclusion We recommend that height2.7 be used for LV mass correction in obese patients.
KW - Echocardiography
KW - Left ventricular hypertrophy
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=85004064476&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85004064476&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2016.11.032
DO - 10.1016/j.ijcard.2016.11.032
M3 - Article
C2 - 27856041
AN - SCOPUS:85004064476
VL - 227
SP - 404
EP - 406
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -