The importance of pelvic lymph node dissection in the elderly population

Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment

Firas Abdollah, Maxine Sun, Shahrokh F. Shariat, Jan Schmitges, Orchidee Djahangirian, Zhe Tian, Claudio Jeldres, Paul Perrotte, Francesco Montorsi, Pierre I. Karakiewicz

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Purpose: National Comprehensive Cancer Network practice guidelines indicate that pelvic lymph node dissection can be omitted at radical cystectomy in elderly patients. We examined the pelvic lymph node dissection rate in patients 80 years old or older and the impact of pelvic lymph node dissection on cancer specific and overall mortality in these patients. Materials and Methods: We examined the records of 11,183 patients treated with radical cystectomy in 17 Surveillance, Epidemiology and End Results registries. We performed univariate and multivariate Cox regression analysis to test the effect of pelvic lymph node dissection on cancer specific and overall mortality. Results: Overall pelvic lymph node dissection was omitted in 25% of patients, including 24.2% younger than 80 years and 30.8% 80 years old or older (p

Original languageEnglish
Pages (from-to)2078-2084
Number of pages7
JournalJournal of Urology
Volume185
Issue number6
DOIs
Publication statusPublished - Jun 2011

Fingerprint

Lymph Node Excision
Practice Guidelines
Urinary Bladder Neoplasms
Population
Cystectomy
Neoplasms
Therapeutics
Mortality
Registries
Epidemiology
Regression Analysis

Keywords

  • aged
  • aged, 80 and over
  • cystectomy
  • lymph node excision
  • urinary bladder

ASJC Scopus subject areas

  • Urology

Cite this

The importance of pelvic lymph node dissection in the elderly population : Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment. / Abdollah, Firas; Sun, Maxine; Shariat, Shahrokh F.; Schmitges, Jan; Djahangirian, Orchidee; Tian, Zhe; Jeldres, Claudio; Perrotte, Paul; Montorsi, Francesco; Karakiewicz, Pierre I.

In: Journal of Urology, Vol. 185, No. 6, 06.2011, p. 2078-2084.

Research output: Contribution to journalArticle

Abdollah, Firas ; Sun, Maxine ; Shariat, Shahrokh F. ; Schmitges, Jan ; Djahangirian, Orchidee ; Tian, Zhe ; Jeldres, Claudio ; Perrotte, Paul ; Montorsi, Francesco ; Karakiewicz, Pierre I. / The importance of pelvic lymph node dissection in the elderly population : Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment. In: Journal of Urology. 2011 ; Vol. 185, No. 6. pp. 2078-2084.
@article{06ce6365907f45da8d0c3d089a9dd33f,
title = "The importance of pelvic lymph node dissection in the elderly population: Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment",
abstract = "Purpose: National Comprehensive Cancer Network practice guidelines indicate that pelvic lymph node dissection can be omitted at radical cystectomy in elderly patients. We examined the pelvic lymph node dissection rate in patients 80 years old or older and the impact of pelvic lymph node dissection on cancer specific and overall mortality in these patients. Materials and Methods: We examined the records of 11,183 patients treated with radical cystectomy in 17 Surveillance, Epidemiology and End Results registries. We performed univariate and multivariate Cox regression analysis to test the effect of pelvic lymph node dissection on cancer specific and overall mortality. Results: Overall pelvic lymph node dissection was omitted in 25{\%} of patients, including 24.2{\%} younger than 80 years and 30.8{\%} 80 years old or older (p",
keywords = "aged, aged, 80 and over, cystectomy, lymph node excision, urinary bladder",
author = "Firas Abdollah and Maxine Sun and Shariat, {Shahrokh F.} and Jan Schmitges and Orchidee Djahangirian and Zhe Tian and Claudio Jeldres and Paul Perrotte and Francesco Montorsi and Karakiewicz, {Pierre I.}",
year = "2011",
month = "6",
doi = "10.1016/j.juro.2011.02.022",
language = "English",
volume = "185",
pages = "2078--2084",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - The importance of pelvic lymph node dissection in the elderly population

T2 - Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment

AU - Abdollah, Firas

AU - Sun, Maxine

AU - Shariat, Shahrokh F.

AU - Schmitges, Jan

AU - Djahangirian, Orchidee

AU - Tian, Zhe

AU - Jeldres, Claudio

AU - Perrotte, Paul

AU - Montorsi, Francesco

AU - Karakiewicz, Pierre I.

PY - 2011/6

Y1 - 2011/6

N2 - Purpose: National Comprehensive Cancer Network practice guidelines indicate that pelvic lymph node dissection can be omitted at radical cystectomy in elderly patients. We examined the pelvic lymph node dissection rate in patients 80 years old or older and the impact of pelvic lymph node dissection on cancer specific and overall mortality in these patients. Materials and Methods: We examined the records of 11,183 patients treated with radical cystectomy in 17 Surveillance, Epidemiology and End Results registries. We performed univariate and multivariate Cox regression analysis to test the effect of pelvic lymph node dissection on cancer specific and overall mortality. Results: Overall pelvic lymph node dissection was omitted in 25% of patients, including 24.2% younger than 80 years and 30.8% 80 years old or older (p

AB - Purpose: National Comprehensive Cancer Network practice guidelines indicate that pelvic lymph node dissection can be omitted at radical cystectomy in elderly patients. We examined the pelvic lymph node dissection rate in patients 80 years old or older and the impact of pelvic lymph node dissection on cancer specific and overall mortality in these patients. Materials and Methods: We examined the records of 11,183 patients treated with radical cystectomy in 17 Surveillance, Epidemiology and End Results registries. We performed univariate and multivariate Cox regression analysis to test the effect of pelvic lymph node dissection on cancer specific and overall mortality. Results: Overall pelvic lymph node dissection was omitted in 25% of patients, including 24.2% younger than 80 years and 30.8% 80 years old or older (p

KW - aged

KW - aged, 80 and over

KW - cystectomy

KW - lymph node excision

KW - urinary bladder

UR - http://www.scopus.com/inward/record.url?scp=79955813699&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955813699&partnerID=8YFLogxK

U2 - 10.1016/j.juro.2011.02.022

DO - 10.1016/j.juro.2011.02.022

M3 - Article

VL - 185

SP - 2078

EP - 2084

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 6

ER -