The importance of pelvic lymph node dissection in the elderly population: Implications for interpreting the 2010 national comprehensive cancer network practice guidelines for bladder cancer treatment

Firas Abdollah, Maxine Sun, Shahrokh F. Shariat, Jan Schmitges, Orchidee Djahangirian, Zhe Tian, Claudio Jeldres, Paul Perrotte, Francesco Montorsi, Pierre I. Karakiewicz

Research output: Contribution to journalArticle

Abstract

Purpose: National Comprehensive Cancer Network practice guidelines indicate that pelvic lymph node dissection can be omitted at radical cystectomy in elderly patients. We examined the pelvic lymph node dissection rate in patients 80 years old or older and the impact of pelvic lymph node dissection on cancer specific and overall mortality in these patients. Materials and Methods: We examined the records of 11,183 patients treated with radical cystectomy in 17 Surveillance, Epidemiology and End Results registries. We performed univariate and multivariate Cox regression analysis to test the effect of pelvic lymph node dissection on cancer specific and overall mortality. Results: Overall pelvic lymph node dissection was omitted in 25% of patients, including 24.2% younger than 80 years and 30.8% 80 years old or older (p

Original languageEnglish
Pages (from-to)2078-2084
Number of pages7
JournalJournal of Urology
Volume185
Issue number6
DOIs
Publication statusPublished - Jun 2011

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Keywords

  • aged
  • aged, 80 and over
  • cystectomy
  • lymph node excision
  • urinary bladder

ASJC Scopus subject areas

  • Urology

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