The in vitro effects of ceftibuten on the host defense mechanism

P. C. Braga, G. Piatti, M. Dal Sasso, S. Maci, F. Blasi

Research output: Contribution to journalArticle

Abstract

The in vitro effects of ceftibuten on human polymorphonuclear leukocyte (PMN) chemotaxis, phagocytosis and chemiluminescence were investigated. PMN from healthy adult donors were incubated for 1 h in medium alone or in medium containing increasing concentrations of ceftibuten (4,8 and 40 times the MIC for Escherichia coli). Up to 40 MIC ceftibuten did not significantly interfere with the function of PMN.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalChemotherapy
Volume40
Issue number1
DOIs
Publication statusPublished - 1994

Fingerprint

Neutrophils
Leukocyte Chemotaxis
Luminescence
Phagocytosis
Tissue Donors
Escherichia coli
In Vitro Techniques
ceftibuten

Keywords

  • Ceftibuten
  • Chemiluminescence
  • Chemotaxis
  • Phagocytosis
  • Polymorphonuclear leukocytes

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Pharmacology (medical)
  • Drug Discovery
  • Pharmacology

Cite this

The in vitro effects of ceftibuten on the host defense mechanism. / Braga, P. C.; Piatti, G.; Dal Sasso, M.; Maci, S.; Blasi, F.

In: Chemotherapy, Vol. 40, No. 1, 1994, p. 37-41.

Research output: Contribution to journalArticle

Braga, PC, Piatti, G, Dal Sasso, M, Maci, S & Blasi, F 1994, 'The in vitro effects of ceftibuten on the host defense mechanism', Chemotherapy, vol. 40, no. 1, pp. 37-41. https://doi.org/10.1159/000239168
Braga, P. C. ; Piatti, G. ; Dal Sasso, M. ; Maci, S. ; Blasi, F. / The in vitro effects of ceftibuten on the host defense mechanism. In: Chemotherapy. 1994 ; Vol. 40, No. 1. pp. 37-41.
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