The in vitro effects of ceftibuten on the host defense mechanism

P. C. Braga, G. Piatti, M. Dal Sasso, S. Maci, F. Blasi

Research output: Contribution to journalArticlepeer-review

Abstract

The in vitro effects of ceftibuten on human polymorphonuclear leukocyte (PMN) chemotaxis, phagocytosis and chemiluminescence were investigated. PMN from healthy adult donors were incubated for 1 h in medium alone or in medium containing increasing concentrations of ceftibuten (4,8 and 40 times the MIC for Escherichia coli). Up to 40 MIC ceftibuten did not significantly interfere with the function of PMN.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalChemotherapy
Volume40
Issue number1
DOIs
Publication statusPublished - 1994

Keywords

  • Ceftibuten
  • Chemiluminescence
  • Chemotaxis
  • Phagocytosis
  • Polymorphonuclear leukocytes

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Pharmacology (medical)
  • Drug Discovery
  • Pharmacology

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