Abstract
The in vivo role of LFA-1 molecule in the immune reaction to a murine retrovirus-induced tumor was investigated. Local and systemic treatment with high doses of anti-LFA-1 monoclonal antibody led to tumor progression by blocking CTL interaction with tumor cells without interferring with CTL generation and localization in the tumor mass.
Original language | English |
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Journal | Leukemia |
Volume | 6 |
Issue number | SUPPL. 3 |
Publication status | Published - 1992 |
ASJC Scopus subject areas
- Hematology
- Cancer Research