The in vivo role of LFA-1 molecule in the immune reaction to a murine retrovirus-induced tumor was investigated. Local and systemic treatment with high doses of anti-LFA-1 monoclonal antibody led to tumor progression by blocking CTL interaction with tumor cells without interferring with CTL generation and localization in the tumor mass.
|Issue number||SUPPL. 3|
|Publication status||Published - 1992|
ASJC Scopus subject areas
- Cancer Research