The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden

Giuseppe Boriani, Gregory Y H Lip, Renato Pietro Ricci, Alessandro Proclemer, Maurizio Landolina, Maurizio Lunati, Luigi Padeletti, Gabriele Zanotto, Giulio Molon, Mauro Biffi, Roberto Rordorf, Fabio Quartieri, Maurizio Gasparini

Research output: Contribution to journalArticlepeer-review

Abstract

AIMS: To evaluate if the increased thromboembolic risk in female patients may be related to a higher burden of atrial fibrillation (AF).METHODS AND RESULTS: Data collected in a prospective observational research of patients implanted with a cardiac implantable electrical device (CIED) were analysed. We included 2398 patients: 489 (20.4%) were female and 1909 (79.6%) were male (oral anticoagulants treatment in 23.2%, independent of gender). During the follow-up (mean 42.8, median 37.7 months), 26 thromboembolic events occurred in 22 patients, with an incidence rate ratio of both stroke and stroke/transient ischemic attack (TIA) significantly higher in females compared with males [2.00, 95% confidence interval (CI) 1.53-2.61, P
Original languageEnglish
JournalEuropace
DOIs
Publication statusPublished - Dec 28 2016

Keywords

  • Journal Article

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