The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden

Giuseppe Boriani; Gregory Y H Lip; Renato Pietro Ricci; Alessandro Proclemer; Maurizio Landolina; Maurizio Lunati; Luigi Padeletti; Gabriele Zanotto; Giulio Molon; Mauro Biffi; Roberto Rordorf; Fabio Quartieri; Maurizio Gasparini

doi:10.1093/europace/euw333

The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden

Giuseppe Boriani, Gregory Y H Lip, Renato Pietro Ricci, Alessandro Proclemer, Maurizio Landolina, Maurizio Lunati, Luigi Padeletti, Gabriele Zanotto, Giulio Molon, Mauro Biffi, Roberto Rordorf, Fabio Quartieri, Maurizio Gasparini

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Abstract

AIMS: To evaluate if the increased thromboembolic risk in female patients may be related to a higher burden of atrial fibrillation (AF).METHODS AND RESULTS: Data collected in a prospective observational research of patients implanted with a cardiac implantable electrical device (CIED) were analysed. We included 2398 patients: 489 (20.4%) were female and 1909 (79.6%) were male (oral anticoagulants treatment in 23.2%, independent of gender). During the follow-up (mean 42.8, median 37.7 months), 26 thromboembolic events occurred in 22 patients, with an incidence rate ratio of both stroke and stroke/transient ischemic attack (TIA) significantly higher in females compared with males [2.00, 95% confidence interval (CI) 1.53-2.61, P

Original language	English
Journal	Europace
DOIs	https://doi.org/10.1093/europace/euw333
Publication status	Published - Dec 28 2016

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10.1093/europace/euw333

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Boriani, G., Lip, G. Y. H., Ricci, R. P., Proclemer, A., Landolina, M., Lunati, M., Padeletti, L., Zanotto, G., Molon, G., Biffi, M., Rordorf, R., Quartieri, F., & Gasparini, M. (2016). The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden. Europace. https://doi.org/10.1093/europace/euw333

Boriani, G, Lip, GYH, Ricci, RP, Proclemer, A, Landolina, M, Lunati, M, Padeletti, L, Zanotto, G, Molon, G, Biffi, M, Rordorf, R, Quartieri, F & Gasparini, M 2016, 'The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden', Europace. https://doi.org/10.1093/europace/euw333

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abstract = "AIMS: To evaluate if the increased thromboembolic risk in female patients may be related to a higher burden of atrial fibrillation (AF).METHODS AND RESULTS: Data collected in a prospective observational research of patients implanted with a cardiac implantable electrical device (CIED) were analysed. We included 2398 patients: 489 (20.4%) were female and 1909 (79.6%) were male (oral anticoagulants treatment in 23.2%, independent of gender). During the follow-up (mean 42.8, median 37.7 months), 26 thromboembolic events occurred in 22 patients, with an incidence rate ratio of both stroke and stroke/transient ischemic attack (TIA) significantly higher in females compared with males [2.00, 95% confidence interval (CI) 1.53-2.61, P",

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T1 - The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden

AU - Boriani, Giuseppe

AU - Lip, Gregory Y H

AU - Ricci, Renato Pietro

AU - Proclemer, Alessandro

AU - Landolina, Maurizio

AU - Lunati, Maurizio

AU - Padeletti, Luigi

AU - Zanotto, Gabriele

AU - Molon, Giulio

AU - Biffi, Mauro

AU - Rordorf, Roberto

AU - Quartieri, Fabio

AU - Gasparini, Maurizio

PY - 2016/12/28

Y1 - 2016/12/28

N2 - AIMS: To evaluate if the increased thromboembolic risk in female patients may be related to a higher burden of atrial fibrillation (AF).METHODS AND RESULTS: Data collected in a prospective observational research of patients implanted with a cardiac implantable electrical device (CIED) were analysed. We included 2398 patients: 489 (20.4%) were female and 1909 (79.6%) were male (oral anticoagulants treatment in 23.2%, independent of gender). During the follow-up (mean 42.8, median 37.7 months), 26 thromboembolic events occurred in 22 patients, with an incidence rate ratio of both stroke and stroke/transient ischemic attack (TIA) significantly higher in females compared with males [2.00, 95% confidence interval (CI) 1.53-2.61, P

AB - AIMS: To evaluate if the increased thromboembolic risk in female patients may be related to a higher burden of atrial fibrillation (AF).METHODS AND RESULTS: Data collected in a prospective observational research of patients implanted with a cardiac implantable electrical device (CIED) were analysed. We included 2398 patients: 489 (20.4%) were female and 1909 (79.6%) were male (oral anticoagulants treatment in 23.2%, independent of gender). During the follow-up (mean 42.8, median 37.7 months), 26 thromboembolic events occurred in 22 patients, with an incidence rate ratio of both stroke and stroke/transient ischemic attack (TIA) significantly higher in females compared with males [2.00, 95% confidence interval (CI) 1.53-2.61, P

KW - Journal Article

U2 - 10.1093/europace/euw333

DO - 10.1093/europace/euw333

M3 - Article

JO - Europace

JF - Europace

SN - 1099-5129

ER -

The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden

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