The indocyanine green method is equivalent to the (99m) Tc-labeled radiotracer method for identifying the sentinel node in breast cancer: A concordance and validation study

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

We assessed concordance between the indocyanine green (ICG) method and 99mTc-radiotracer method to identify the sentinel node (SN). One hundred thirty-four women with clinically node-negative early breast cancer received preoperative injection of 99mTc-labeled tracer for lymphoscintigraphy, followed by intraoperative injection of ICG for detection of SNs. The 134 patients provided 246 SNs, detected by one or both methods. The two methods were concordant for 230/246 (93.5A%) SNs and discordant for 16 (6.5A%) SNs. The ICG method detected 99.6A% of all SNs. Fluorescent lymphangiography with ICG allows an easy identification of axillary SNs, at a frequency not inferior to that of the radiotracer method and can be used alone to reliably identify SNs.

Original languageEnglish
Title of host publicationFluorescence Imaging for Surgeons: Concepts and Applications
PublisherSpringer International Publishing
Pages255-266
Number of pages12
ISBN (Print)9783319156781, 9783319156774
DOIs
Publication statusPublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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