The inflammatory response in cerebral ischemia: Focus on cytokines in stroke patients

Maria Grazia De Simoni, Paolo Milia, Michela Barba, Ada De Luigi, Lucilla Parnetti, Virgilio Gallai

Research output: Contribution to journalArticlepeer-review

Abstract

This paper outlines the characteristics of the inflammatory reaction to brain ischemia with the aim of underlying its relevance and specific implication in the pathogenesis of this disorder. The attention is focused on cytokines, major inflammatory mediators produced in the central nervous system and in the periphery in the context of the response to brain injury. The available data on cytokines in patients with stroke are reviewed to investigate the characteristics of the inflammatory response in human samples and to elucidate if the production of these inflammatory molecules may be related to the clinical outcome.

Original languageEnglish
Pages (from-to)535-542
Number of pages8
JournalClinical and Experimental Hypertension
Volume24
Issue number7-8
DOIs
Publication statusPublished - Oct 2002

Keywords

  • Cytochines
  • Inflammation
  • Peripheral markers

ASJC Scopus subject areas

  • Internal Medicine

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