The influence of lysophosphatidic acid on the immunophenotypic differentiation of human monocytes into dendritic cells

Angelo Martino, Elisabetta Volpe, Patrizia Morena Baldini

Research output: Contribution to journalArticlepeer-review

Abstract

Lysophosphatidic acid (LPA), a naturally occurring phospholipid, has been suggested to have an immunoregulatory role. We investigated the effect of LPA on differentiation of human monocytes into dendritic cells (DC). We found that LPA affects DC differentiation from monocytes by blocking the expression of CD1a molecules on their surface in a dose-dependent manner.

Original languageEnglish
Pages (from-to)1273-1274
Number of pages2
JournalHaematologica
Volume91
Issue number9
Publication statusPublished - Sep 2006

Keywords

  • CD1A
  • Dendritic cells
  • Differentiation
  • LPA

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'The influence of lysophosphatidic acid on the immunophenotypic differentiation of human monocytes into dendritic cells'. Together they form a unique fingerprint.

Cite this