The influence of night-time hypertension on left ventricular mechanics

Marijana Tadic, Cesare Cuspidi, Biljana Pencic-Popovic, Vera Celic, Giuseppe Mancia

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective The aim of this study was to evaluate left ventricular (LV) mechanics in individuals with daytime, night-time and day-nighttime hypertension. Methods This cross-sectional study included 272 untreated subjects who underwent 24-hour ambulatory blood pressure monitoring and complete two-dimensional echocardiographic examination including strain analysis. According to current guidelines, night-time hypertension was defined as nocturnal systolic blood pressure ≥ 120 mm Hg and/or diastolic blood pressure ≥ 70 mm Hg and day-time hypertension as systolic blood pressure ≥ 135 mm Hg and/or diastolic blood pressure ≥ 85 mm Hg. Results The study sample included 61 normotensive subjects (22%), 77 isolated daytime hypertension (28%), 40 isolated night-time hypertension (15%) and 94 day-nighttime hypertension (35%). LV longitudinal and circumferential strain gradually and significantly decreased from normotensive subjects across patients with isolated daytime and night-time hypertension to hypertensive individuals with persistent hypertension. Radial strain was similar between the observed groups. LV twist increased from normotensive subjects across isolated daytime and night-time hypertensive patients to day-nighttime hypertensive individuals. Hypertensive patients with day-nighttime and night-time hypertension are significantly more associated with decreased longitudinal and circumferential strain than hypertensive patients with isolated day-time hypertension and normotension. Conclusion LV mechanics gradually deteriorated from normotensive controls, across isolated day- and night-time hypertension, to day-nighttime hypertension. Patients with night-time and day-nighttime hypertension are associated with higher risk of LV mechanical dysfunction than normotensives and day-time hypertensives.

Original languageEnglish
Pages (from-to)443-448
Number of pages6
JournalInternational Journal of Cardiology
Volume243
DOIs
Publication statusPublished - Sep 15 2017

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Mechanics
Hypertension
Ambulatory Blood Pressure Monitoring
Left Ventricular Dysfunction
Cross-Sectional Studies
Guidelines

Keywords

  • Left ventricle
  • Nocturnal hypertension
  • Strain

ASJC Scopus subject areas

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

Cite this

The influence of night-time hypertension on left ventricular mechanics. / Tadic, Marijana; Cuspidi, Cesare; Pencic-Popovic, Biljana; Celic, Vera; Mancia, Giuseppe.

In: International Journal of Cardiology, Vol. 243, 15.09.2017, p. 443-448.

Research output: Contribution to journalArticle

Tadic, Marijana ; Cuspidi, Cesare ; Pencic-Popovic, Biljana ; Celic, Vera ; Mancia, Giuseppe. / The influence of night-time hypertension on left ventricular mechanics. In: International Journal of Cardiology. 2017 ; Vol. 243. pp. 443-448.
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N2 - Objective The aim of this study was to evaluate left ventricular (LV) mechanics in individuals with daytime, night-time and day-nighttime hypertension. Methods This cross-sectional study included 272 untreated subjects who underwent 24-hour ambulatory blood pressure monitoring and complete two-dimensional echocardiographic examination including strain analysis. According to current guidelines, night-time hypertension was defined as nocturnal systolic blood pressure ≥ 120 mm Hg and/or diastolic blood pressure ≥ 70 mm Hg and day-time hypertension as systolic blood pressure ≥ 135 mm Hg and/or diastolic blood pressure ≥ 85 mm Hg. Results The study sample included 61 normotensive subjects (22%), 77 isolated daytime hypertension (28%), 40 isolated night-time hypertension (15%) and 94 day-nighttime hypertension (35%). LV longitudinal and circumferential strain gradually and significantly decreased from normotensive subjects across patients with isolated daytime and night-time hypertension to hypertensive individuals with persistent hypertension. Radial strain was similar between the observed groups. LV twist increased from normotensive subjects across isolated daytime and night-time hypertensive patients to day-nighttime hypertensive individuals. Hypertensive patients with day-nighttime and night-time hypertension are significantly more associated with decreased longitudinal and circumferential strain than hypertensive patients with isolated day-time hypertension and normotension. Conclusion LV mechanics gradually deteriorated from normotensive controls, across isolated day- and night-time hypertension, to day-nighttime hypertension. Patients with night-time and day-nighttime hypertension are associated with higher risk of LV mechanical dysfunction than normotensives and day-time hypertensives.

AB - Objective The aim of this study was to evaluate left ventricular (LV) mechanics in individuals with daytime, night-time and day-nighttime hypertension. Methods This cross-sectional study included 272 untreated subjects who underwent 24-hour ambulatory blood pressure monitoring and complete two-dimensional echocardiographic examination including strain analysis. According to current guidelines, night-time hypertension was defined as nocturnal systolic blood pressure ≥ 120 mm Hg and/or diastolic blood pressure ≥ 70 mm Hg and day-time hypertension as systolic blood pressure ≥ 135 mm Hg and/or diastolic blood pressure ≥ 85 mm Hg. Results The study sample included 61 normotensive subjects (22%), 77 isolated daytime hypertension (28%), 40 isolated night-time hypertension (15%) and 94 day-nighttime hypertension (35%). LV longitudinal and circumferential strain gradually and significantly decreased from normotensive subjects across patients with isolated daytime and night-time hypertension to hypertensive individuals with persistent hypertension. Radial strain was similar between the observed groups. LV twist increased from normotensive subjects across isolated daytime and night-time hypertensive patients to day-nighttime hypertensive individuals. Hypertensive patients with day-nighttime and night-time hypertension are significantly more associated with decreased longitudinal and circumferential strain than hypertensive patients with isolated day-time hypertension and normotension. Conclusion LV mechanics gradually deteriorated from normotensive controls, across isolated day- and night-time hypertension, to day-nighttime hypertension. Patients with night-time and day-nighttime hypertension are associated with higher risk of LV mechanical dysfunction than normotensives and day-time hypertensives.

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