The influence of plasma technology coupled to chemical grafting on the cell growth compliance of 3D hydroxyapatite scaffolds

Laura Russo, Stefano Zanini, Paolo Giannoni, Elena Landi, Anna Vila, Monica Sandri, Claudia Riccardi, Rodolfo Quarto, Silvia M. Doglia, Francesco Nicotra, Laura Cipolla

Research output: Contribution to journalArticle

Abstract

The development of advanced materials with biomimetic features in order to elicit desired biological responses and to guarantee tissue biocompatibility is recently gaining attention for tissue engineering applications. Bioceramics, such as hydroxyapatite-based biomaterials are now used in a number of different applications throughout the body, covering all areas of the skeleton, due to their biological and chemical similarity to the inorganic phases of bones. When bioactive sintered hydroxyapatite (HA) is desired, biomolecular modification of these materials is needed. In the present work, we investigated the influence of plasma surface modification coupled to chemical grafting on the cell growth compliance of HA 3D scaffolds.

Original languageEnglish
Pages (from-to)2727-2738
Number of pages12
JournalJournal of Materials Science: Materials in Medicine
Volume23
Issue number11
DOIs
Publication statusPublished - Nov 2012

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering

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    Russo, L., Zanini, S., Giannoni, P., Landi, E., Vila, A., Sandri, M., Riccardi, C., Quarto, R., Doglia, S. M., Nicotra, F., & Cipolla, L. (2012). The influence of plasma technology coupled to chemical grafting on the cell growth compliance of 3D hydroxyapatite scaffolds. Journal of Materials Science: Materials in Medicine, 23(11), 2727-2738. https://doi.org/10.1007/s10856-012-4727-y