The ins and outs of osteopontin

Claudia Chiodoni, Sabina Sangaletti, Claudio Tripodo, Mario P. Colombo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The continuous remodeling of progressing tumors demands non-physiologic production of extracellular matrix (ECM) proteins. Among them, osteopontin (OPN) has been largely involved in tumor progression and metastasis. We have recently discovered a new mechanism for OPN in the metastatic spread of mammary carcinoma providing local immunosuppression at the seeding site.

Original languageEnglish
Pages (from-to)1-2
Number of pages2
JournalOncoImmunology
Volume4
Issue number3
DOIs
Publication statusPublished - 2015

Fingerprint

Osteopontin
Extracellular Matrix Proteins
Immunosuppression
Neoplasms
Breast Neoplasms
Neoplasm Metastasis

Keywords

  • Metastasis
  • Myeloid-derived suppressor cells
  • Osteopontin

ASJC Scopus subject areas

  • Immunology and Allergy
  • Oncology
  • Immunology

Cite this

The ins and outs of osteopontin. / Chiodoni, Claudia; Sangaletti, Sabina; Tripodo, Claudio; Colombo, Mario P.

In: OncoImmunology, Vol. 4, No. 3, 2015, p. 1-2.

Research output: Contribution to journalArticle

Chiodoni, Claudia ; Sangaletti, Sabina ; Tripodo, Claudio ; Colombo, Mario P. / The ins and outs of osteopontin. In: OncoImmunology. 2015 ; Vol. 4, No. 3. pp. 1-2.
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