The invertebrate phagocytic immunocyte: Clues to a common evolution of immune and neuroendocrine systems

Enzo Ottaviani, Claudio Franceschi

Research output: Contribution to journalArticle

148 Citations (Scopus)

Abstract

In invertebrates, lower vertebrates and higher vertebrates, a common pool of highly conserved molecules appears to mediate phagocytosis, the stress response and inflammation. Here, Enzo Ottaviani and Claudio Franceschi propose an evolutionary hypothesis based on an integrated network of adaptive mechanisms that are critical for survival. The macrophage plays a pivotal role in this process.

Original languageEnglish
Pages (from-to)169-174
Number of pages6
JournalImmunology Today
Volume18
Issue number4
DOIs
Publication statusPublished - Apr 1997

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Neurosecretory Systems
Invertebrates
Vertebrates
Immune System
Phagocytosis
Macrophages
Inflammation

ASJC Scopus subject areas

  • Immunology

Cite this

The invertebrate phagocytic immunocyte : Clues to a common evolution of immune and neuroendocrine systems. / Ottaviani, Enzo; Franceschi, Claudio.

In: Immunology Today, Vol. 18, No. 4, 04.1997, p. 169-174.

Research output: Contribution to journalArticle

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