The Italian external quality assessment scheme in classical cytogenetics: Four years of activity

G. Floridia, V. Falbo, F. Censi, F. Tosto, M. Salvatore, A. Baroncini, P. Battaglia, A. Conti, E. Donti, R. La Starza, L. Nitsch, M. Pierluigi, G. Piombo, F. Susca, M. Mancini, C. Mecucci, E. Calzolari, F. Dagna Bricarelli, G. Guanti, D. Taruscio

Research output: Contribution to journalArticle

Abstract

Background: The Italian external quality assessment scheme in classical cytogenetics was started in 2001 as an activity funded by the National Health System and coordinated by the Italian Public Institute of Health. Objectives: The aim of our work is to present data from the first 4 years of activity, 2001-2004. Methods: Italian cytogenetics public laboratories were enrolled on a voluntary basis, and this nationwide program covered prenatal, postnatal and oncological diagnosis. The scheme is annual and retrospective; a panel of experts reviewed the quality of images and reports in order to assess technical, analytical and interpretative performance. Results: Over the 4-year period, the number of participating laboratories increased: from 36 in 2001, 46 in 2002, 49 in 2003 to 51 in 2004. The overall technical performance was satisfactory. Inadequacy or lack of information in reporting was the most frequent analytical inaccuracy identified in all parts of the scheme. However, the percentage of complete reports increased significantly during the period: by 36% in postnatal diagnosis between 2001 and 2004 (p <0.001) and by 42% in oncological diagnosis between 2002 and 2004 (p = 0.003). Conclusions: Our experience reveals that participation in external quality assessment programs has significant advantages, helping to standardize and to assure quality in cytogenetic testing.

Original languageEnglish
Pages (from-to)295-303
Number of pages9
JournalCommunity Genetics
Volume11
Issue number5
DOIs
Publication statusPublished - May 2008

Fingerprint

Cytogenetics
Public Health
Health

Keywords

  • Classical cytogenetics
  • External quality assessment

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

The Italian external quality assessment scheme in classical cytogenetics : Four years of activity. / Floridia, G.; Falbo, V.; Censi, F.; Tosto, F.; Salvatore, M.; Baroncini, A.; Battaglia, P.; Conti, A.; Donti, E.; La Starza, R.; Nitsch, L.; Pierluigi, M.; Piombo, G.; Susca, F.; Mancini, M.; Mecucci, C.; Calzolari, E.; Dagna Bricarelli, F.; Guanti, G.; Taruscio, D.

In: Community Genetics, Vol. 11, No. 5, 05.2008, p. 295-303.

Research output: Contribution to journalArticle

Floridia, G, Falbo, V, Censi, F, Tosto, F, Salvatore, M, Baroncini, A, Battaglia, P, Conti, A, Donti, E, La Starza, R, Nitsch, L, Pierluigi, M, Piombo, G, Susca, F, Mancini, M, Mecucci, C, Calzolari, E, Dagna Bricarelli, F, Guanti, G & Taruscio, D 2008, 'The Italian external quality assessment scheme in classical cytogenetics: Four years of activity', Community Genetics, vol. 11, no. 5, pp. 295-303. https://doi.org/10.1159/000121401
Floridia, G. ; Falbo, V. ; Censi, F. ; Tosto, F. ; Salvatore, M. ; Baroncini, A. ; Battaglia, P. ; Conti, A. ; Donti, E. ; La Starza, R. ; Nitsch, L. ; Pierluigi, M. ; Piombo, G. ; Susca, F. ; Mancini, M. ; Mecucci, C. ; Calzolari, E. ; Dagna Bricarelli, F. ; Guanti, G. ; Taruscio, D. / The Italian external quality assessment scheme in classical cytogenetics : Four years of activity. In: Community Genetics. 2008 ; Vol. 11, No. 5. pp. 295-303.
@article{0301b6a82dd54c1190a045c623bea0b4,
title = "The Italian external quality assessment scheme in classical cytogenetics: Four years of activity",
abstract = "Background: The Italian external quality assessment scheme in classical cytogenetics was started in 2001 as an activity funded by the National Health System and coordinated by the Italian Public Institute of Health. Objectives: The aim of our work is to present data from the first 4 years of activity, 2001-2004. Methods: Italian cytogenetics public laboratories were enrolled on a voluntary basis, and this nationwide program covered prenatal, postnatal and oncological diagnosis. The scheme is annual and retrospective; a panel of experts reviewed the quality of images and reports in order to assess technical, analytical and interpretative performance. Results: Over the 4-year period, the number of participating laboratories increased: from 36 in 2001, 46 in 2002, 49 in 2003 to 51 in 2004. The overall technical performance was satisfactory. Inadequacy or lack of information in reporting was the most frequent analytical inaccuracy identified in all parts of the scheme. However, the percentage of complete reports increased significantly during the period: by 36{\%} in postnatal diagnosis between 2001 and 2004 (p <0.001) and by 42{\%} in oncological diagnosis between 2002 and 2004 (p = 0.003). Conclusions: Our experience reveals that participation in external quality assessment programs has significant advantages, helping to standardize and to assure quality in cytogenetic testing.",
keywords = "Classical cytogenetics, External quality assessment",
author = "G. Floridia and V. Falbo and F. Censi and F. Tosto and M. Salvatore and A. Baroncini and P. Battaglia and A. Conti and E. Donti and {La Starza}, R. and L. Nitsch and M. Pierluigi and G. Piombo and F. Susca and M. Mancini and C. Mecucci and E. Calzolari and {Dagna Bricarelli}, F. and G. Guanti and D. Taruscio",
year = "2008",
month = "5",
doi = "10.1159/000121401",
language = "English",
volume = "11",
pages = "295--303",
journal = "Community Genetics",
issn = "1422-2795",
publisher = "S. Karger AG",
number = "5",

}

TY - JOUR

T1 - The Italian external quality assessment scheme in classical cytogenetics

T2 - Four years of activity

AU - Floridia, G.

AU - Falbo, V.

AU - Censi, F.

AU - Tosto, F.

AU - Salvatore, M.

AU - Baroncini, A.

AU - Battaglia, P.

AU - Conti, A.

AU - Donti, E.

AU - La Starza, R.

AU - Nitsch, L.

AU - Pierluigi, M.

AU - Piombo, G.

AU - Susca, F.

AU - Mancini, M.

AU - Mecucci, C.

AU - Calzolari, E.

AU - Dagna Bricarelli, F.

AU - Guanti, G.

AU - Taruscio, D.

PY - 2008/5

Y1 - 2008/5

N2 - Background: The Italian external quality assessment scheme in classical cytogenetics was started in 2001 as an activity funded by the National Health System and coordinated by the Italian Public Institute of Health. Objectives: The aim of our work is to present data from the first 4 years of activity, 2001-2004. Methods: Italian cytogenetics public laboratories were enrolled on a voluntary basis, and this nationwide program covered prenatal, postnatal and oncological diagnosis. The scheme is annual and retrospective; a panel of experts reviewed the quality of images and reports in order to assess technical, analytical and interpretative performance. Results: Over the 4-year period, the number of participating laboratories increased: from 36 in 2001, 46 in 2002, 49 in 2003 to 51 in 2004. The overall technical performance was satisfactory. Inadequacy or lack of information in reporting was the most frequent analytical inaccuracy identified in all parts of the scheme. However, the percentage of complete reports increased significantly during the period: by 36% in postnatal diagnosis between 2001 and 2004 (p <0.001) and by 42% in oncological diagnosis between 2002 and 2004 (p = 0.003). Conclusions: Our experience reveals that participation in external quality assessment programs has significant advantages, helping to standardize and to assure quality in cytogenetic testing.

AB - Background: The Italian external quality assessment scheme in classical cytogenetics was started in 2001 as an activity funded by the National Health System and coordinated by the Italian Public Institute of Health. Objectives: The aim of our work is to present data from the first 4 years of activity, 2001-2004. Methods: Italian cytogenetics public laboratories were enrolled on a voluntary basis, and this nationwide program covered prenatal, postnatal and oncological diagnosis. The scheme is annual and retrospective; a panel of experts reviewed the quality of images and reports in order to assess technical, analytical and interpretative performance. Results: Over the 4-year period, the number of participating laboratories increased: from 36 in 2001, 46 in 2002, 49 in 2003 to 51 in 2004. The overall technical performance was satisfactory. Inadequacy or lack of information in reporting was the most frequent analytical inaccuracy identified in all parts of the scheme. However, the percentage of complete reports increased significantly during the period: by 36% in postnatal diagnosis between 2001 and 2004 (p <0.001) and by 42% in oncological diagnosis between 2002 and 2004 (p = 0.003). Conclusions: Our experience reveals that participation in external quality assessment programs has significant advantages, helping to standardize and to assure quality in cytogenetic testing.

KW - Classical cytogenetics

KW - External quality assessment

UR - http://www.scopus.com/inward/record.url?scp=44249119914&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44249119914&partnerID=8YFLogxK

U2 - 10.1159/000121401

DO - 10.1159/000121401

M3 - Article

C2 - 18493128

AN - SCOPUS:44249119914

VL - 11

SP - 295

EP - 303

JO - Community Genetics

JF - Community Genetics

SN - 1422-2795

IS - 5

ER -